Pharmaceutical Intermediates

Product Name: 11-Bromo-1-undecanol Synonyms: 11-Bromo-1-hydroxyundecane;11-Bromoundecan-1-ol;11 , -BroMo-1- undecanol puruM, >=99.0% (AT);11-Bromo-1-undecanol purum;11-BroMo-1-undecanol, 97% 10GR;11-BroMo-1-undecanol, 97% 50GR;1-Bromo-11-hydroxyundecane;UNDECAMETHYLENE BROMOHYDRIN Product Categories: Alcohols;Building Blocks;C11 to C30+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;omega-Bromoalkanols;omega- Functional Alkanols, Carboxylic Acids, Amines & Halides;Linear hydrocarbon series;OLED materials,pharm chemical,electronic Melting point  46-49 °C(lit.) Boiling point  165-170 °C1 mm Hg(lit.) density  1.1887 (rough estimate) refractive index  1.5290 (estimate) Fp  >230 °F storage temp.  0-10°C solubility  chloroform: soluble50mg/mL, clear to slightly hazy, colorless to dark yellow pka 15.20±0.10(Predicted) form  Crystals or Crystalline Powder color  White to beige Water Solubility  Insoluble in water.

Minimum Order: 10 long tons

Product Name: (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-p , henylbutane Synonyms: (2R, 3S)-1,2-EPOXY-3-N-(TERT-BUTOXYCARBONYL)AMINO-4-PHE , NYLBUTANE; (2r,3s)-3-(n-boc-amino)-1-oxirane-4- , phenylbutane;(2R,3S)-3-(tert- Butoxycarbonyl)am , ino-1,2-epoxy-4-phenylbutane;[1(S)-BENZYL-2(R),3-E , POXYPROPYL]- CARBAMIC ACID TERT-BUTYL ESTER;THREO-N-BOC-L-PHENYLALANINE EPOXIDE;TERT-BUTYL (1S)-1-[(2R)-OXIRAN-2-YL]-2-PHENYLETHYLCARBAMA , TE;Tert-Butyl[(1S)-1-(2R)-Oxiranyl-2- Phenyleth , yl]carbamate;Carbamic acid,[(1S)-1-(2R)-oxiranyl-2-phenylethyl]-,1,1- dimethylethyl ester Product Categories: Heterocycles;chiral;Chiral Amino Epoxides;Aromatics Compounds;Aromatics;Chiral Reagents Boiling point  398.8±25.0 °C(Predicted) density  1.118±0.06 g/cm3(Predicted) pka 12.19±0.46(Predicted) Chemical Properties: White Crystalline Powder Uses: Atazanavir intermediate. Enantiomer R Uses: Atazanavir, Amprenavir Intermediate

Minimum Order: 10 long tons

Product Name: 2,3-DIFLUORO-5-(TRIFLUOROMETHYL)PYRIDINE Synony , ms: 2,3-DIFLUORO-5-(TRIFLUOROMETHYL)PYRIDINE;alpha,alp , ha,alpha,5,6- Pentafluoro-3-picoline;2,3-Difluo , ro-5-(trifluoromethyl)pyridine >;Pyridine, 2,3- difluoro-5-(trifluoromethyl)- Product Categories: alkyl Fluorine Melting point  -20°C Boiling point  104°C density  1,47 g/cm3

Minimum Order: 10 long tons

Product Name: 4'-(Trifluoromethyl)acetophenone Synonyms: 1-(4-Trifluoromethyl-phenyl)-ethanone;1-[4- (Tr , ifluoromethyl)phenyl]ethanone;Ethanone, 1-[4-(trifluoromethyl)phenyl]-;1-[4- (Trifluoro , methyl)phenyl]ethan-1-one;4'-(TRIFLUOROMETHYL) , ACETOPHENONE;4- (TRIFLUOROMETHYL)ACETOPHENONE;4 , -ACETYLBENZOFLUORIDE;4-ACETYLBENZOTRIFLUORIDE P , roduct Categories: Aromatic Acetophenones & Derivatives (substituted);ketone;Trifluoromethylbenzene serise;Aromatics Melting point  30-33 °C(lit.) Boiling point  79-80 °C8 mm Hg(lit.) density  0.92 refractive index  1.4604 Fp  184 °F storage temp.  Flammables area form  Low Melting Solid color  White to faintly yellow Chemical Properties: White to faintly yellow low melting solid Uses: A labelled acetophenone with selective antimycobacterial activity.

Minimum Order: 10 long tons

Product Name: 1-(2,2-diMethoxyethyl)-5-Methoxy-6-(Methoxycarbony , l)-4-oxo-1,4- dihydropyridine-3-carboxylic acid Synonyms: 1-(2,2-Dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo , -2,5- pyridinedicarboxylic acid 2-methyl ester;1-[2,2-bis(methyloxy)ethyl]-5- (methyloxy , )-6-[(methyloxy)carbonyl]-4-oxo-1,4-dihydro-3-pyri , dinecarboxylic acid;1- (2,2-diMethoxyethyl)-5-Methoxy-6-(Metho , xycarbonyl)-4-oxo-1,4-dihydropyridine-3- carbox , ylic acid;2,5-Pyridinedicarboxylic acid, 1-(2,2-dimethoxyethyl)-1,4-dihydro- 3-methoxy-4 , -oxo-, 2-methyl ester;Dolutegravir Intermediates3;1-(2,2- Dimethoxyethyl)-1,4-dihy , dro-3-methoxy-4-oxo-2,5-pyridinedicarboxylic acid 2-methyl este;1-(2,2-dimethoxyethyl)-5-methoxy-4-oxo-1, , 4-dihydropyridine-3,6-dicarboxylic acid-6-methyl ester;Dulotegravir Me-N-4 Boiling point  474.1±45.0 °C(Predicted) density  1.36±0.1 g/cm3(Predicted) pka 5.56±0.40(Predicted)

Minimum Order: 10 long tons

Product Name: Tribromobenzene Synonyms: 1,3,5-tribromo-benzen;Benzene,1,3,5-tribromo-;I,3, , 5- TribrombenzolC&W%16;Tribromobenzene;1,3,5-TR , IBROMOBENZENE;Phloroglucinol Impurity 27;Tribromobenzene,98%;1,3,5-TRIBROMOBENZENE OEKANAL, 250 MG Product Categories: Aryl;C6;Aromatic Hydrocarbons (substituted) & Derivatives;Organics;Benzene derivates;Halogenated Hydrocarbons Melting point  117-121 °C (lit.) Boiling point  271 °C (lit.) density  2.3515 (estimate) refractive index  1.6340 (estimate) Fp  271°C storage temp.  Room temperature. solubility  Soluble in benzene, chloroform, and ether (Weast, 1986) form  Powder form  Solid color  Almost white to orange-brown Water Solubility  Soluble in hot ethanol and acetic acid. Insoluble in water. Chemical Properties: Lump powder Uses: Intermediate in drug manufacturing; organic synthesis; internal standard in analysis of aqueous samples.

Minimum Order: 10 long tons

Product Name: Xanthone Synonyms: 9-OXOXANTHENE;9-XANTHENONE;BENZOPHENONE OXIDE;Genicide;Xanthene, 9- Oxo-;Xanthenone;9-xanthenore;Xanthone, 99% (9-Xanthenone) Product Categories: Inhibitors;Bioactive Small Molecules;Building Blocks;C13 to C14;Carbonyl Compounds;Cell Biology;Chemical Synthesis;Hypericum perforatum (St John′;Ketones;Nutrition Research;Organic Building Blocks;Phytochemicals by Plant (Food/Spice/Herb);s wort);X;Drug bulk Melting point  172-174 °C(lit.) Boiling point  349-350 °C730 mm Hg(lit.) density  1.1607 (rough estimate) refractive index  1.6000 (estimate) Fp  350-351°C storage temp.  Store below +30°C. form  neat Water Solubility  It is Soluble in water (partly), chloroform, hot Toluene, ether (slightly), and hot alcohol. Chemical Properties: off-white powder Uses: Acts as an inhibitor of human cancer cell lines. Definition: ChEBI: The parent compound of the xanthone class consisting of xanthene bearing a single oxo substituent at position 9. Definition A colorless crystalline organic compound found as a pigment in gentians and other flowers. It is used as an insecticide and in making dyestuffs.

Minimum Order: 10 long tons

Product Name: (Bromomethyl)cyclopropane Synonyms: CPMBr;Cyclopropylcarbinyl bromide;Bromo(cyclopropyl)methane;1- (Bromometh , yl)cyclopropane, 95+%;(Bromomethyl)cyclopropane,Cyclopropylmethyl bromide;(Bromomethyl)cyclopr;(Bromomethyl)cycl , opropane,96%;Cyclopropane Methyl Chloride Product Categories: Methyl Halides;Halides;Methyl Halides;Ring Systems;Cycloalkanes;Miscellaneous Reagents Melting point  87-90 °C Boiling point  105-107 °C(lit.) density  1.392 g/mL at 25 °C(lit.) refractive index  n20/D 1.457(lit.) Fp  107 °F storage temp.  0-6°C form  Liquid Specific Gravity 1.392 color  Clear colorless to slightly colored Water Solubility  Not miscible in water. Uses: (Bromomethyl)cyclopropane is used in the synthesis of 1,4-dienes by iron- catalyzed cross-coupling with alkenyl Grignard reagents. Description: (Bromomethyl) cyclopropane is a cyclopropane derivative. It can be used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1, 4-dienes via iron-catalyzed cross- coupling with alkenyl Grignard reagents. Chemical Properties: Colorless to yellow liquid

Minimum Order: 10 long tons

Product Name: Atropic acid Synonyms: 2-Phenylpropenoic acid;2-PHENYLPROP-2-ENOIC ACID;Ipratropium EP Impurity D;Ipratropium Bromide EP Impurity D (2-Phenyl Acrylic Acid);Ipratropium Bromide EP Impurity D;2-Phenylacrylic acid 95%;2-PHENYLACRYLIC ACID;ALPHA- PHENYLACRYLIC ACID Product Categories: Aromatics, Impurities;Pharmaceutical Intermediates Melting point  106-107° Boiling point  bp ~267° with partial decompn density  1.0061 (rough estimate) refractive index  1.5049 (estimate) pka 3.86±0.11(Predicted) Water Solubility  1.3g/L(20 ºC) Chemical Properties: White Solid Uses: Atropic acid is an Impurity of Ipratropium bromide (I740500) and Atropine Sulfate (A794625).

Minimum Order: 10 long tons

Product Name: Methoxypolyethylene glycols Synonyms: 2-ethanediyl),.alpha.-methyl-.omega.-hydroxy-Poly( , oxy-1;ETHYLENE GLYCOL 750 MONOMETHYL ETHER POLYMER;ETHYLENE GLYCOL 5000 MONOMETHYL ETHER POLYMER;ETHYLENE GLYCOL 550 MONOMETHYL ETHER POLYMER;ETHYLENE GLYCOL 350 MONOMETHYL ETHER POLYMER;ETHYLENE GLYCOL 1900 MONOMETHYL ETHER POLYMER;METHOXY POLYETHYLENE GLYCOL 750;Methoxypolyethylene glycols Product Categories: PEG;Cosmetic;Cosmetic Ingredients & Chemicals;Non-Ionic Detergents;Polydispersed PEG;construction;Detergents;Detergents N to Z;Hydroxy;Materials Science;Monofunctional PEGs;Poly(ethylene glycol) and Poly(ethylene oxide);Polymer Science;Optimization Reagents;Polymers;X-Ray Crystallography;Protein Structural Analysis;Proteomics Melting point  60-64 °C Boiling point  >200°C/760mmHg Vensity  1.094 g/mL at 25 °C Vapor density  >1 (vs air) Vapor pressure  0.05 mm Hg ( 20 °C) Refractive index  n20/D 1.459 Fp  268 °C Storage temp.  ?20°C Solubility  H2O: 50 mg/mL at 25 °C, clear, colorless Form  semisolid Specific Gravity 1.094 Color  White to pale yellow PH 5.5-7.0 (25℃, 50mg/mL in H2O) Water Solubility  Slightly miscible with water. Chemical Properties: varies from viscous liquid to white flakes, depending Uses: enteric coating controlled release and enteric release coatings

Minimum Order: 10 long tons

Product Name: 2,4,8,10-Tetraoxaspiro[5.5]undecane, 3,9-diethylidene- Synonyms: 2,4,8,10-Tetraoxaspiro[5.5]undecane, 3,9-diethylidene- Boiling point  357.1±42.0 °C(Predicted) density  1.14±0.1 g/cm3(Predicted)

Minimum Order: 10 long tons

PProduct Name: DL-Aspartic acid Synonyms: H-D-ASP-OH;H-DL-ASP-OH;DL-ASPARTIC ACID;DL-ASPARAGINIC ACID;D,L- ASP;DL-AMINOSUCCINIC ACID;DL-2-AMINOBUTANEDIOIC ACID;D-ASPARAGINIC ACID Product Categories: nutritional supplement;amino acid;Amino Acids Derivatives;aspartic acid;organic acids;pharmaceutical intermediate;Aspartic acid [Asp, D];alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids Melting point  300 °C alpha  [α]D20 0±0.3° (c=5, dil. HCl) Boiling point  245.59°C (rough estimate) density  1.6622 refractive index  1.4540 (estimate) storage temp.  Store at RT. solubility  SOLUBLE pka 2.28±0.23(Predicted) form  Crystalline Low Melting Mass color  Yellow Odor acid taste Water Solubility  SOLUBLE Chemical Properties: White crystalline powder Uses: Food additive. Uses: DL-Aspartic acid is used in studies on factors and conditions that enhance semen and sperm quality. Its conjugate base D-aspartate has potential use as a therapeutic agent in the treatment of schizophrenia-related symptoms.

Minimum Order: 10 long tons

Product Name: 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Synonyms: 5-Methoxye-2-mercaplobenzinidazole;TIMTEC-BB SBB000219;5-METHOXY- 1H-BENZO[D]IMIDAZOLE-2-THI , OL;5-Methoxybenzimidazole-2-thiol;5-METHOXY-2- , THIOBENZIMIDAZOLE;5-METHOXY-2-MERCAPTOBENZIMIDAZOL , E;5-METHOXY-2- BENZIMIDAZOLETHIOL;2-MERCAPTO-5- , METHOXY-1H-BENZIMIDAZOLE Product Categories: OLED materials,pharm chemical,electronic;Aromatics;BENZIMIDAZOLE;Be , nzimidazoles;Building Blocks;Sulfur & Selenium Compounds;BUILDING BLOCKS;Imidazol&Benzimidazole;(intermediate of omeprazole);Heterocyclic Building Blocks Melting point  261-263 °C(lit.) Boiling point  309.4±44.0 °C(Predicted) density  1.2425 (rough estimate) refractive index  1.5690 (estimate) storage temp.  Refrigerator, Under Inert Atmosphere pka 10.13±0.30(Predicted) form  Powder color  Off-white to light yellow-brown Water Solubility  insoluble Sensitive  Air Sensitive Description: 2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5- methoxy-2[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfonyl]-1H- benzimidazole, 5-methoxy-2[[(4-methoxy-3, 5-dimethylpyridin-2-yl-1-oxide) methyl] sulfonyl]-1H-benzimidazole as well as tris[μ-1,2- bis(diphenylphosphino)ethane]-1:2

Minimum Order: 10 long tons

Product Name: Chloromethyl isopropyl carbonate Synonyms: CMIC;CHLOROMETHYL ISOPROPYL CARBONATE;I-PROPYL CHLOROMETHYL CARBONATE;Chloromethyl (1-Methylethyl) Carbonate;Chloromethyl-2-propyl carbonate;L- Propylchloromethylcarbonate;Chloro , methyl Isopropyl Carbonate (JMC-1);Carbonic acid, chloromethyl 1-methylethyl ester Product Categories: Miscellaneous Reagents;Pharmaceutical Intermediates Boiling point  66 °C(Press: 16 Torr) density  1.14 refractive index  1.4110-1.4150 storage temp.  Refrigerator, Under Inert Atmosphere Chemical Properties: Clear Colourless Liquid

Minimum Order: 10 long tons