Pharmaceutical Chemicals

Epitalon (also known as Epithalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in the pineal gland. It was synthesized by Vladimir Khavinson, a Russian professor and gerontologist, whose research focused on the development of peptide preparations used to restore function in various organs in order to prevent and reverse the aging process. He is currently the Director of the Saint Petersburg Institute of Bioregulation and Gerontology. Epitalon is considered the "fountain of youth" peptide. It is a tetra-peptide, which means that it is composed of four amino acid chains. The peptide is used to regulate the cell cycle during telomerase activity. Telomerase, also called telomere terminal transferase, is an enzyme made of protein and RNA subunits that elongates chromosomes. When telomerase activity is not present (when we age), our cells age. Our telomeres get shorter and begin to die off. If telomerase is activated in our cells, our telomeres lengthen, the cell continues to grow and divide, delaying the aging process. (UT Southwestern Medical Lab) CAS No.: 307297-39-8

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TB-500 is a synthetic version of a naturally occurring protein fragment called thymosin beta-4. In animal studies, it has shown potential in promoting wound healing, reducing inflammation, and aiding tissue regeneration. These findings have led some to experiment with TB-500 for human use, hoping to reap similar benefits

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4-Trifluoromethylnicotinic acid is a light to dark yellow solid that is useful as a synthetic intermediate. It can be used to prepare pyridinecarboxamide as a palindromic inhibitor of HCV NS5B polymerase. It can also be used to synthesize pyrazolylformamide as an inhibitor of Ca2 + release-activated Ca2 + (CRAC) channels. Brand: Soarwin CAS No.: 158063-66-2 EC Number: 623-902-1 Molecular Formula: C7H4F3NO2 Density: 1.484±0.06 g/cm3(Predicted) Melting point: 146-148 °C(lit.) Boiling point: 290.4±40.0 °C(Predicted)

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Sodium tert-butoxide is a white to off-white powder, widely used as a strong base in chemical, pharmaceutical, pesticide and organic synthesis in condensation, rearrangement and ring opening reactions. Stable at room temperature and pressure, avoid contact with strong reducing agent, moisture, air and acid. Slightly harmful to water, avoid letting undiluted or large quantities of the product come into contact with groundwater, watercourses or sewage systems; if there is no government permit, do not discharge the material into the surrounding environment. Used as organic synthesis intermediates, pharmaceutical intermediates; as a strong base widely used in chemical, pharmaceutical, pesticide and other organic synthesis in the condensation, rearrangement and ring-opening reaction. Brand: Soarwin CAS No.: 865-48-5 EC Number: 212-741-9 Molecular Formula: C4H9NaO Density: 1,104 g/cm3 Melting point: 180 °C Boiling point: 180°C/1mmHg Flash point: 12°C

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3-Aminobenzotrifluoride is a transparent light yellow liquid, it is the intermediate of herbicide fluazifop, fluroxypyr and pyroflumizone, and also a pharmaceutical intermediate, such as for the synthesis of butyl flumefenacet, monifluoric acid ester, fluphenazine, trifluoro-propazine, flusarium and so on. It is an important intermediate of dyestuff, medicine and pesticide. Used in the manufacture of antipsychotic drugs Fluphenazine, Trifluoroalanine, Trifluoperazine, etc.. Used in the synthesis of herbicides fluridone, fluroxypyr, Norflurazon, etc., used for the prevention and control of broad- leaved weeds and perennial weeds in wheat fields, cotton fields, and so on. Brand: Soarwin CAS No.: 98-16-8 EC Number: 202-643-4 Molecular Formula: C7H6F3N Density: 1.29 g/mL at 25 °C(lit.) Melting point: 5 °C Boiling point: 187 °C(lit.) Flash point: 185 °F

Triphenylmethyl chloride is one of the basic organic raw materials commonly used in the field of non-pharmaceutical chemical industry. In the process of organic chemical industry and drug synthesis, it can be used as the selective protecting group of primary hydroxyl group, amine group and sulfhydryl group in compounds such as nucleoside, monosaccharides or polysaccharides, as well as the basic chemicalbook agent in the synthesis of polypeptide. After using triphenylchloromethane as a protective reagent in the process of organic chemical and drug synthesis, in the process of removing the triphenylmethyl protective group in acidic alcohol solution, usually generates triphenylmethyl alkyl ether such as triphenylmethyl methyl ether, triphenylmethyl ethyl ether, triphenylmethyl propyl ether and other byproducts. Brand: Soarwin CAS No.: 76-83-5 EC Number: 200-986-4 Molecular Formula: C19H15Cl Density: 1.1088 (rough estimate) Melting point: 109-112 °C(lit.) Boiling point: 230-235 °C20 mm Hg(lit.) Flash point: 230-235°C/20mm

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Pyrroloquinoline quinone disodium salt is a water-soluble quinone compound that has a strong antioxidant capacity. It is isolated from cultures of methylotrophic bacteria and tissues of mammals. This essential nutrient is vital for mammals, playing a crucial role in enhancing immune function. Pyrroloquinoline quinone disodium salt can act as an antioxidant and there is strong evidence that PQQ may play an important role in important pathways of cell signaling. PQQ plays a variety of physiological roles, such as promoting growth and reproduction and providing neurological and cardiovascular protection. Pyrroloquinoline quinone disodium salt protects cells from oxidative damage and increases the mitochondrial membrane potential, which is essential for the production of ATP. It also stimulates enzyme activities, such as glutathione peroxidase and glutathione reductase, and prevents lipid peroxidation of human serum. This compound also inhibits radiation-induced cellular damage by preventing DNA strand breakage. It may be effective in treating diseases related to oxidative stress, such as diabetes and cancer. Brand: Soarwin CAS No.: 122628-50-6 Molecular Formular:C14H4N2Na2O8 EC Numbe: 209-118-9 Boiling point: 1018.6°C at 760 mmHg Flash point: 569.8°C

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Minoxidil is a type of oral drug that is clinically used to lower blood pressure, and it is also called Loniten and piperidine diamine. Minoxidil is an antihypertensive drug that is clinically used to treat intractable, primary or renal hypertension. It can also be used to treat severe hypertension that does not respond well to other antihypertensive drugs, but it needs to be used in combination with diuretic drugs to prevent water and sodium retention, and combined use with beta receptor blockers may increase its curative effects and reduce adverse effects. Minoxidil is also used to prevent grease-type alopecia and on livestock. Minoxidil is a type of potassium channel opener and can directly relax smooth vascular muscles and has a strong small artery dilating effect. It can reduce peripheral resistance, dilate blood vessels, and lower blood pressure while having no effect on blood volume, thus promoting venous return. In addition, due to reflective regulation and positive frequency effects, it can increase cardiac output and heart rate, but will not cause orthostatic hypotension. Brand: Soarwin CAS No.: 38304-91-5 EC Number: 253-874-2 Molecular Formula: C9H15N5O Density: 1.1651 (rough estimate) Boiling point: 348.61°C (rough estimate) Melting point:272-274 °C (dec.) (lit.)

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2,4-Diamino pyrimidine-3-oxide is a valuable organic synthetic reagent for preparing pyrimidines and in making hair loss and skin care compositions. It is used in hair care formulations to prevent increased hair loss. Brand: Soarwin CAS No.: 74638-76-9 Molecular Formula: C4H6N4O EC Number: 616-121-2 Density: 1.69±0.1 g/cm3(Predicted) Boiling point: 475.5±37.0 °C(Predicted) Flash point: 241.374°C

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Glabridin is a natural whitening agent isolated from glycyrrhizin flavone. Glabridin has strong antibacterial effects and can prevent inflammation, pigmentation, and rough skin caused by ultraviolet rays. It can also remove superoxide ions and inhibit hemolysis caused by hydrogen peroxide. Moreover, it can inhibit the activity of tyrosinase and the conversion of dopachrome, making it an effective and environmentally-friendly additive for whitening and freckle removal in cosmetics. Glabridin is a compound extracted from Licorice (root) shows properties that are cytotoxic, antimicrobial, estrogenic and anti-proliferative. Brand: Soarwin CAS No.: 59870-68-7 Molecular Formula: C20H20O4 EC Number: 611-908-7 Density: 1.257±0.06 g/cm3(Predicted) Boiling point: 518.6±50.0 °C(Predicted) Melting point: 154-155°C Flash point: 267°C

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Levodopa is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brain, levodopa is decarboxylated to dopamine and stimulates the dopaminergic receptors, thereby compensating for the depleted supply of endogenous dopamine seen in Parkinson's disease. Levodopa is an immediate precursor of dopamine and product of tyrosine hydroxylase. It derived from vanillin is widely used for treatment of Parkinson’s disease, most often in combination with peripheral decarboxylase inhibitors such as benserazide and carbidopa. Brand: Soarwin CAS No.: 59-92-7 Molecular Formula: C9H11NO4 EC Number:200-445-2 Density: 1.3075 (rough estimate) Boiling point: 334.28°C (rough estimate) Melting point: 276-278 °C (lit.)

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L-carnitine is a naturally available compound that plays a significant role in fatty acid oxidation and energy production in the human body. It is majorly found in skeletal and cardiac muscles of mammals and facilitates the transport of long chain fatty acids into mitochondria. L-carnitine has been widely used in functional food as a new type of nutritional fortification agent, especially as an additive of infant formula food, athlete food and slimming and bodybuilding food. L-carnitine as a commodity is mainly its hydrochloride, tartrate and magnesium citrate. Brand: Soarwin CAS No.: 541-15-1 Molecular Formula: C7H15NO3 EC Number: 208-768-0 Density: 10.64 g/cm3 Boiling point: 287.5°C (rough estimate) Melting point: 197-212 °C(lit.)

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Pyrrolidinyl Diaminopyrimidine Oxide is a hair growth stimulant that can be used to treat hair loss. It can also be used in cosmetics to invent a dermocosmetic composition having a whitening or dark circle removal or anti- glare effect by containing a pyrrolidinyl diaminopyrimidine oxide compound as an active ingredient. Brand: Soarwin CAS No.: 55921-65-8 Molecular Formula: C8H13N5O EC Number: 618-347-7 Density: 1.60 Boiling point: 549.3±60.0 °C(Predicted)) Melting point: 278 °C (DEC.)

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Azelaic acid is a topical antiacne agent which exerts its therapeutic action through a myriad of antimicrobial, antiproliferative and cytostatic effects. In vitro, azelaic acid hasbeen shown to inhibit DNA polymerases in several tumor cell lines. Application: A.Polymers and related materials: Esters of this dicarboxylic acid find applications in lubrication and plasticizers. With hexamethylenediamine azelaic acid forms Nylon - 6,9, which finds specialized uses as a plastic. B.Medical: Azelaic acid is used to treat mild to moderate acne, both comedonal acne and inflammatory acne . It belongs to a class of medication called dicarboxylic acids. It works by killing acne bacteria that infect skin pores. It also decreases the production of keratin, which is a natural substance that promotes the growth of acne bacteria Azelaic acid is also used as a topical gel treatment for rosacea, due to its ability to reduce inflammation . It clears the bumps and swelling caused by Rosacea. Azelaic acid has been used for treatment of skin pigmentation including melasma and post inflammatory hyper pigmentation , particularly in those with darker skin types. It has been recommended as an alternative to hydroquinone (HQ). As a tyrosinase inhibitor, azelaic acid reduces synthesis of melanin. Brand: Soarwin CAS No.: 123-99-9 Molecular Formula: C9H16O4 EC Number: 204-669-1 Density: 1.029 g/cm3 Boiling point: 286 °C100 mm Hg(lit.) Melting point: 98 °C Flash point: 215°C

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