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Other Organic Chemicals
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| Summary of 6/16/25 20:45 GMT: | >> Show Compact View |
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Guanidine hydrochloride (GdnHCl) is a potent chaotropic agent that is widely used in biochemistry and molecular biology. The compound has the chemical formula CH5N3•HCl and was first synthesized in the late 19th century. Its discovery stemmed from the study of guanidine, a compound found in guano, which led to the development of its hydrochloride salt to improve solubility and stability. Researchers soon realized its unique properties, making it a valuable tool in a variety of scientific applications. Guanidine hydrochloride consists of a guanidine molecule with a central carbon atom double-bonded to a nitrogen atom, single-bonded to two other nitrogen atoms, and paired with a chloride ion. This structure gives it high solubility in water, allowing it to interact effectively with biomolecules. GdnHCl is a white crystalline solid that is hygroscopic and highly soluble in water and alcohol, making it easy to handle in a laboratory setting. GdnHCl denatures proteins by disrupting hydrogen bonds and hydrophobic interactions, which causes the protein structure to unfold. This denaturation is essential for studying protein folding and stability and for refolding proteins from inclusion bodies in recombinant protein production. After denaturation, GdnHCl can be gradually removed to study the protein refolding process, providing insights into the mechanisms of protein folding and misfolding, which is critical to understanding diseases associated with protein aggregation. The chaotropic effect of guanidine hydrochloride involves disrupting the hydrogen-bonding network of water molecules, thereby disrupting the native conformation of proteins and nucleic acids. This disruption results in unfolding of proteins and denaturation of nucleic acid structures, facilitating their study and manipulation in a variety of biochemical and molecular biology applications. GdnHCl is used in RNA extraction protocols to inhibit ribonucleases (RNases) that degrade RNA. Its chaotropic properties denature RNases, ensuring the integrity of RNA samples for downstream applications such as reverse transcription and sequencing. In molecular biology, GdnHCl is used in DNA purification procedures to remove proteins and other contaminants. Its ability to denature proteins facilitates the isolation of high-purity DNA for cloning, sequencing, and other genetic analyses. GdnHCl is used to temporarily inactivate enzymes, allowing researchers to study their mechanisms of action and interactions with substrates and inhibitors. This application is critical in enzymology and drug discovery. Guanidine hydrochloride is considered hazardous and should be handled with care. It is irritating to the skin, eyes, and respiratory tract. Appropriate personal protective equipment, including gloves and goggles, should be used. In addition, guanidine hydrochloride solutions should be prepared in a well- ventilated area or under a fume hood to avoid inhalation of dust or vapors. Brand: Soarwin CAS No.: 50-01-1 EC number:200-002-3 Molecular Formula: CH5N3.HCl Density: 1.18g/mLat 25°C(lit.) Boiling point:132.9oC at 760 mmHg Melting point:180-185°C(lit.) Flashing point: 34.2 °C
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Dicyanodiammonia, abbreviated as dicy or DCD. It is an organic substance with the chemical formula of c2h4n4. It is a dimer of cyanamide and a cyano derivative of guanidine. Chemical formula c2h4n4. White crystalline powder. Soluble in water, alcohol, ethylene glycol and dimethylformamide, almost insoluble in ether and benzene. Stable when dry. It is a guanidine in which one of the amino hydrogens of guanidine itself is substituted by a cyano group. It is used in the manufacture of fertilizers, pharmaceuticals, explosives, oil well drilling muds, and dyestuffs. It has a role as a curing agent, a flame retardant, a fertilizer, an explosive and a nitrification inhibitor. It is a member of guanidines and a nitrile. The application of nitrification inhibitors has been used as a strategy to promote N utilization efficacy and reduce N2O emissions in paddy Dicyandiamide (DCD) as a widely used nitrification inhibitor inhibits the activity of ammonium-oxidizing bacteria which results in longer ammonium retention and reduces the production of NO2?in soils. DCD efficacy was found to be related to DCD concentration, temperature, moisture, pH, and organic matter content. Studies have shown that leaching DCD from agricultural soils into aquatic ecosystems can strongly change the community composition of benthic stream bacteria and algae and influence stream nutrient cycling stoichiometry. Literature on the mechanisms and benefits of nitrification inhibitors is extensive but there are very few studies focused on the influence of DCD application on other microbes in paddy system. Brand: Soarwin CAS No.: 461-58-5 EC number:207-312-8 Molecular Formula: C2H4N4 Density: 1.40 Boiling point:229.8oC at 760mmHg Melting point:208-211°C(lit.) Flashing point: 92.8°C
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2-Carboxy-3-nitrobenzoic ethyl ester is a commonly used organic synthetic intermediate. It can also be used as a raw material for pigments and dyes. Brand: Soarwin CAS No.: 16533-45-2 Molecular Formula: C10H9NO6 Density: 1.421±0.06 g/cm3 (20 ºC 760 Torr) Boiling point:415.5±35.0 °C(Predicted) Melting point:157℃
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2-Chlorocinnamic acid is a kind of trans-cinnamate. It is used in organic synthesis. Brand: Soarwin CAS No.: 3752-25-8 EC number:223-154-2 Molecular Formula: C9H7ClO2 Density: 1.2377 (rough estimate Boiling point:260.71°C (rough estimate) Melting point:208-210 °C(lit.)
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![2,2-Bis[4-(4-aminophenoxy)phenyl]propane](javascript:openWnd('https://www.imexbb.com/Images/10894690/13080-86-9.jpg', 'Image', 540, 720, 0, 0, 0, 1, 1, 0, 0))
2,2-Bis[4-(4-aminophenoxy)phenyl] propane (BAPP) can be used for: (1) Preparation of polyimides. The glass transition temperature of this new polyimide is about 225-230°C. It has the typical yield of thermoplastic polymers. It has a typical thermoplastic polymer yield behaviour, which is very different from other polyimides. The elongation at break was 6% and 29% for polyamide and polyimide, respectively. (2) Curing epoxy resin (ER) and poly(?-caprolactone) (PCL) for the preparation of crystalline thermoset blends. (3) Constructing dental resin composites. Brand: Soarwin CAS No.: 13080-86-9 EC Number: 235-985-8 Molecular Formula: C27H26N2O2 Density: 1.178±0.06 g/cm3(Predicted) Boiling point:587.1±50.0 °C(Predicted) Melting point:127-130 °C(lit.)
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2,5-Dichlorobenzophenones can be used as starting materials for general, pharmaceutical and polymer synthesis. For example, using such compounds to prepare substituted para-polyphenylenes should proceed readily by metal- catalyzed aryl coupling of the 2,5-dichlorophenyl group of these compounds. Polyphenylenes formed from these compounds will have pendant side groups comprising the carbonyl, and the aryl or pyridyl group bonded thereto. Brand: Soarwin CAS No.: 16611-67-9 EC Number: 605-427-1 Molecular Formula: C13H8Cl2O Density: 1.311±0.06 g/cm3(Predicted) Boiling point:240-260 °C Melting point:87-88°C Flash point:156.4 °C
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3-Butylglutaric acid is an intermediate in the synthesis of pregabalin.Pregabalin is approved by the United States Food and Drug Administration (FDA) to treat neuropathic pain associated with diabetic peripheral neuropathy, spinal cord injury, and postherpetic neuralgia. Pregabalin is FDA-approved for the treatment of fibromyalgia. Pregabalin also has FDA approval as adjunctive therapy for partial-onset seizures in adults with epilepsy. Brand: Soarwin CAS No.: 75143-89-4 EC Number: 1592732-453-0 Molecular Formula: C9H16O4 Density: 1.126±0.06 g/cm3(Predicted) Boiling point:326.2±15.0 °C(Predicted) Melting point:47 °C Flash point:165.289ºC
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1,4-Benzodioxane-2-carboxylic acid is mainly used in the field of organic synthesis. It can also be used as an additive for paints, resins and plastics. Brand: Soarwin CAS No.: 34385-93-8 EC Number: 1533716-785-6 Molecular Formula: C9H8O4 Density: 1.379 g/cm3 Boiling point:347.2ºC at 760 mmHg Melting point: 126-130ºC(lit.) Flash point:145.4ºC
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1,3-Dimethylbarbituric acid is used as a catalyst in the Knoevenagel condensation of a series of aromatic aldehydes. It is also used in the synthesis of 5-aryl-6-(alkyl- or aryl-amino)-1,3-dimethylfuro [2,3-d]pyrimidine derivatives and enantioselective synthesis of isochromene pyrimidinedione derivatives. Brand: Soarwin CAS No.: 769-42-6 EC Number: 212-211-7 Molecular Formula: C6H8N2O3 Density: 1.322 g/cm3 Boiling point: 228.1oC at 760 mmHg Melting point: 121-123°C(lit.) Flash point: 95.3 ºC
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Trifluoroacetamide can be used to prepare N, O- bis(trimethylsilyl)trifluoroacetamide. N, O- bis(trimethylsilyl)trifluoroacetamide is an important pharmaceutical intermediate, mainly used as a neutral silylating agent in the silylation protection of amino groups, amino acids, phenols, carboxylic acids and enols. As a mild neutral silylating agent, it not only has high reaction activity and good selectivity, but also has the advantages of high reaction yield and simple post-processing. Brand: Soarwin CAS No.:431-47-0 EC Number：207-074-5 Molecular Formula:C3H3F3O2 Density：1.4176 (estimate) Melting point:65-70 °C (lit.) Boiling point:162.5 °C (lit.) Flash point:162-164°C
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2-Chloro-6-nitrotoluene is used as a reagent in the synthesis of 3-Chloro-2- methylaniline (C367805); a herbicide intermediate. Brand: Soarwin CAS No.: 83-42-1 EC Number: 201-475-9 Molecular Formula: C7H6ClNO2 Density: 1.3246 (rough estimate) Boiling point: 238 °C (lit.) Melting point: 34-36 °C (lit.) Flash point: 257°F
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As an important organic chemical raw material, ETFA is widely used in the synthesis of organic fluorine compounds, medicine, pesticides, liquid crystals and dyes. The specific applications are as follows: (1) In medicine, it is mainly used in the production of anti-inflammatory drugs for osteoarthritis, anti-tumor drugs for the treatment of colon and rectal cancer, and cardiovascular and cerebrovascular drugs such as lenoprolol; (2) In pesticides, it is mainly used to manufacture cell division inhibitors and is used to kill grass and broadleaf weeds in cotton and peanut fields; (3) In organic synthesis, ETFA is often used to protect amino groups because it has a low removal rate under mild conditions. Brand: Soarwin CAS No.:383-63-1 EC Number：206-851-6 Molecular Formula:C4H5F3O2 Density：1.194 g/mL at 25 °C(lit.) Melting point:-78 °C Boiling point:60-62 °C(lit.) Flash point:30 °F
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Nonapeptide-1 is a skin lightening peptide, derived from the melanocyte stimulating hormone (MSH). It prevents the activity of tyrosine in the melanocytes, melanin synthesis inhibition and helps to even out your skin tone by lessening hyper-pigmentation. This process reduces the formation of unwanted pigmentation, allowing for the control over skin tone and brown spots. Brand: Soarwin CAS No.: 158563-45-2 Molecular Formula: C61H87N15O9S Density: 1.38±0.1 g/cm3
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Polymer and copolymers used in surgical adhesives, coatings, and lacquers; modifier for alkyd and polystyrene resins; plasticizer for nitrocellulose and other plastics; chemical intermediate. Brand: Soarwin CAS No.: 109-53-5 EC Number: 203-678-8 Molecular Formula: C6H12O Density: 0.769 Boiling point: -112 °C Melting point: 83 °C Flash point: 8°F
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Methyl trifluoroacetate is an important trifluoromethyl-containing reagent and building block. It has important applications in the synthesis of organic fluorine compounds. It can condense with esters, ketones, nitriles, etc. containing α-hydrogen, and further synthesize complex organic compounds containing trifluoromethyl, especially heterocyclic compounds. It can also be used as a protecting reagent for amino groups, etc. Brand: Soarwin CAS No.:431-47-0 EC Number：207-074-5 Molecular Formula:C3H3F3O2 Density：1.273 g/mL at 25 °C (lit.) Melting point:-78 °C Boiling point:43-43.5 °C (lit.) Flash point:19 °F
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SOURCE: Import-Export Bulletin Board (https://www.imexbb.com/)
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