Organic Intermediates

Beta-Diphosphopyridine nucleotide (β-DPN) was discovered in the mid-20th century during research into cellular metabolism and energy production. Its identification stemmed from investigations into the role of coenzymes in biochemical reactions, particularly those involved in oxidative phosphorylation and the electron transport chain. β-DPN was isolated from cellular extracts and characterized as an essential cofactor involved in electron transfer reactions within cells. This pivotal discovery shed light on the mechanisms underlying cellular respiration and energy metabolism, leading to a deeper understanding of biological processes at the molecular level. β-DPN serves as a crucial cofactor in numerous enzymatic reactions involved in cellular respiration, glycolysis, and fatty acid oxidation. It plays a central role in transferring electrons from metabolic intermediates to the electron transport chain, facilitating ATP synthesis and energy production in cells. Researchers utilize β-DPN in studies exploring metabolic pathways, enzyme kinetics, and the regulation of cellular energy metabolism. Measurement of β-DPN levels in biological samples can provide valuable insights into cellular energy status and metabolic health. Abnormal levels of β-DPN may indicate metabolic disorders such as mitochondrial dysfunction, diabetes, or metabolic syndrome. Diagnostic assays based on β-DPN analysis help clinicians diagnose and monitor these conditions, guiding treatment strategies and patient care. Understanding the role of β-DPN in cellular metabolism is essential for the development of therapeutics targeting metabolic diseases. Pharmaceutical companies utilize β-DPN as a target for drug discovery and development, aiming to modulate its activity to treat conditions like diabetes, obesity, and neurodegenerative disorders. Research into β-DPN metabolism and its dysregulation in disease states informs the design of novel pharmacological interventions.β-DPN finds applications in biotechnological processes for the production of biofuels, pharmaceuticals, and industrial chemicals. Enzymatic reactions utilizing β-DPN as a cofactor enable the synthesis of valuable compounds through biocatalysis. Biotechnologists engineer microorganisms and enzymes to optimize β-DPN-dependent pathways for efficient bioproduction of desired products, contributing to sustainable and environmentally friendly manufacturing practices.β-DPN metabolism plays a role in nutrient utilization and energy metabolism in organisms. Studies investigating dietary factors that influence β-DPN levels provide insights into nutritional strategies for optimizing metabolic health and preventing chronic diseases. Understanding β- DPN's role in nutrient metabolism informs dietary recommendations and nutritional interventions aimed at improving overall health and well-being. Brand: Soarwin CAS No.:53-84-9 EC Number: 200-184-4 Molecular Formula: C21H27N7O14P2 Melting point : 140-142°C

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β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). Brand: Soarwin CAS No.: 606-68-8 EC Number: 210-123-3 Molecular Formula: C21H30N7NaO14P2 Density :1.955 at 20℃ Melting point : 140-142°C

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Nicotinamide Riboside Chloride is the chloride salt form of nicotinamide riboside(NR).NR is a new form pyridine-nucleoside of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide(NAD) or NAD+ . Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride. Nicotinamide riboside chloride increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside chloride is used in dietary supplements. Brand: Soarwin CAS No.: 23111-00-4 EC Number: 200-184-4 Molecular Formula: C11H15ClN2O5

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NMNH (reduced Nicotinamide Mononucleotide) is a new potent NAD+ precursor. It is a new form of NMN, can increase NAD levels to a much higher extent. NMNH is a fluorescent molecule, in contrast to NMN. The molecular formulae for NMNH is C11H17N2O8P and it is also known as 1-(5-O-phosphono-beta-D- ribofuranosyl) -1,4-dihydropyridine-3-carboxamide Reduced nicotinamide mononucleotide. Brand: Soarwin CAS No.: 108347-85-9 Molecular Formula: C11H18N2NaO8P

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Nicotinamide ribonucleotide (NMN) is a nucleotide derived from ribose and nicotinamide, a form of vitamin B3. The discovery of NMN dates back to early studies on the biosynthesis of nicotinamide adenine dinucleotide (NAD+), a crucial coenzyme in cellular metabolism. Researchers identified NMN as an intermediate in the NAD+ biosynthesis pathway. One of the most prominent applications of NMN is in the field of anti-aging research. NMN supplementation has been shown to increase NAD+ levels in cells, which decline with age. Higher NAD+ levels are associated with improved mitochondrial function, enhanced DNA repair, and better cellular health. NMN plays a crucial role in regulating metabolic processes, making it a promising candidate for treating metabolic disorders. By boosting NAD+ levels, NMN enhances the function of enzymes involved in energy production and lipid metabolism. Research has shown that NMN supplementation can improve insulin sensitivity, reduce inflammation, and mitigate the effects of obesity and type 2 diabetes in animal models. The neuroprotective properties of NMN have been explored in the context of neurodegenerative diseases such as Alzheimer's and Parkinson's. NAD+ is essential for neuronal survival and function, and its depletion is linked to neurodegeneration. NMN supplementation has been shown to protect neurons, enhance cognitive function, and reduce neuroinflammation in animal models. Cardiovascular health is another area where NMN shows promise. NAD+ levels are critical for maintaining the function of the cardiovascular system, including the health of blood vessels and the heart. Research indicates that NMN can improve endothelial function, enhance blood flow, and reduce the risk of atherosclerosis. NMN's ability to enhance mitochondrial function and energy production has also led to interest in its potential to improve athletic performance. By increasing NAD+ levels, NMN may boost endurance, reduce fatigue, and enhance recovery in athletes. Brand: Soarwin CAS No.: 1094-61-7 EC Number: 214-136-5 Molecular Formula: C11H15N2O8P Melting point: 166 °C（dec.）

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2-Amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride is a chemical compound notable for its distinctive structure and wide range of applications in both research and industry. This compound, commonly referred to by its chemical name, is a derivative of acetamide with a trifluoroethyl group and an amino substituent. The discovery of 2-amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride stemmed from efforts to explore the chemical properties and applications of trifluoroethyl derivatives. The introduction of the trifluoroethyl group into the acetamide structure was a strategic choice aimed at enhancing the compound's reactivity and stability. The trifluoroethyl group, known for its electron-withdrawing properties, imparts unique characteristics to the molecule, making it valuable in various chemical contexts. The synthesis of 2-amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride typically involves the reaction of 2-aminoacetamide with 2,2,2-trifluoroethyl chloride under controlled conditions. The resulting hydrochloride salt form is commonly used to facilitate the handling and solubility of the compound in aqueous solutions. This preparation method ensures the production of a high- purity product suitable for diverse applications. One of the primary applications of 2-amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride is in medicinal chemistry. The trifluoroethyl group enhances the molecule's metabolic stability and influences its interaction with biological targets. As a result, this compound has been explored for its potential use in drug development. The presence of the amino group allows for further chemical modifications, leading to the synthesis of novel compounds with improved pharmacological properties. Researchers have investigated its potential as a building block for pharmaceuticals aimed at treating various diseases. In addition to its role in drug development, 2-amino-N-(2,2,2- trifluoroethyl)acetamide hydrochloride finds applications in the field of agrochemicals. The trifluoroethyl group contributes to the compound's ability to interact with biological systems, making it a candidate for designing new agrochemical agents. Its properties can be leveraged to develop herbicides or insecticides with enhanced efficacy and selectivity. Another notable application of this compound is in the field of materials science. The trifluoroethyl group imparts unique physical and chemical properties to the molecule, making it useful for creating advanced materials. By incorporating 2-amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride into polymer matrices or other material systems, researchers can design materials with specific characteristics, such as increased thermal stability or chemical resistance. Overall, 2-amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride is a versatile chemical substance with significant implications for medicinal chemistry, agrochemical development, and materials science. Its unique combination of functional groups makes it a valuable tool for researchers and industry professionals seeking to explore new chemical transformations and applications. Brand: Soarwin CAS No.: 1171331-39-7 EC Number: 806-518-0 Molecular Formula: C4H8ClF3N2O

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Methyl-4-acetylbenzoic acid can be used as an organic synthesis intermediate and a pharmaceutical intermediate, and is mainly applied in the laboratory research process and chemical production process. Brand: Soarwin CAS No.:55860-35-0 EC Number:856-079-4 Molecular Formula: C10H10O3 Density: 1.189±0.06 g/cm3 Boiling point: 352.7±30.0 °C

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1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoro-et , hanone is a chemical compound of interest due to its unique structure and potential applications in various fields of organic synthesis and materials science. This compound consists of a trifluoroethanone group attached to a phenyl ring that is substituted with chlorine and fluorine atoms, providing a highly reactive electrophilic center. The presence of multiple halogen atoms in the structure enhances the compound's reactivity and makes it a useful intermediate for the synthesis of more complex molecules. Its chemical properties and the presence of the trifluoroethanone group suggest that it can be utilized in reactions such as nucleophilic substitution, electrophilic aromatic substitution, and as a building block for the development of functionalized compounds. The discovery of 1-(3,5-dichloro-4-fluorophenyl)-2,2,2-trifluoro-et , hanone is part of ongoing research into the synthesis of halogenated compounds, which are of great importance in organic chemistry due to their reactivity and stability. The halogenated aromatic ring structure provides a versatile platform for designing molecules with tailored properties, such as enhanced solubility, stability, and reactivity. The trifluoroethanone moiety, in particular, is known for its ability to participate in nucleophilic substitution reactions, making it a valuable intermediate in the creation of other fluorinated compounds. In terms of application, 1-(3,5-dichloro-4-fluorophenyl)-2,2,2-trifluoro- ethanone is often employed in the synthesis of fluorinated organic molecules, which have significant applications in the pharmaceutical, agrochemical, and materials industries. The fluorine atoms in the structure impart unique electronic and steric properties to the molecule, which can be harnessed to develop compounds with enhanced bioactivity and specificity. In the pharmaceutical industry, for example, fluorinated compounds are widely used due to their ability to increase the stability, bioavailability, and metabolic resistance of drugs. This particular compound may serve as an important intermediate in the design of new fluorine-containing pharmaceuticals with improved therapeutic profiles. Additionally, the compound's potential as a building block for the synthesis of agrochemicals cannot be overlooked. Fluorine-containing agrochemicals have become increasingly important in pest control and agricultural applications because they tend to exhibit greater efficacy and environmental stability compared to non-fluorinated counterparts. The ability to incorporate trifluoroethanone and halogenated aromatic groups into agrochemical structures could lead to the development of more effective pesticides, herbicides, or fungicides with desirable characteristics such as low toxicity and high target selectivity. The reactivity of 1-(3,5-dichloro-4-fluorophenyl)-2,2,2-trifluoro-et , hanone also extends to materials science, where it could be used in the design of functionalized polymers or specialty materials. Fluorinated compounds are known for their excellent chemical resistance, thermal stability, and hydrophobicity, making them ideal candidates for high-performance materials. By incorporating the trifluoroethanone group into polymeric materials, it is possible to enhance their properties, making them suitable for use in demanding environments, such as coatings, electronic components, and other advanced applications. In conclusion, 1-(3,5-dichloro-4-fluorophenyl)-2,2,2-trifluoro-et , hanone is a valuable compound with a wide range of applications in organic synthesis, pharmaceuticals, agrochemicals, and materials science. Its unique combination of trifluoroethanone and halogenated aromatic components offers a powerful platform for the development of new and improved compounds with desirable properties. As research in these fields continues, it is likely that the applications of this compound will expand, contributing to advancements in various industries. Brand: Soarwin CAS No.: 1190865-44-1 EC Number:829-719-5 Molecular Formula: C8H2Cl2F4O Melting point: 1.577±0.06 g/cm3 (20 ºC 760 Torr) Boiling point: 124.7±27.3 ºC

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Calcium Levomethylfolate is a biologically active form of folate, the calcium salt of L-methylfolate. It is an essential compound in the fields of nutrition and medicine, notable for its role in various biological processes. Calcium Levomethylfolate was born out of research into the role of folate in human health. Folate is a B vitamin that is essential for DNA synthesis, repair, and cellular function. Unlike folic acid, which is the synthetic form of folate, L-methylfolate is a naturally occurring, biologically active form that the body can use directly. The discovery and development of Calcium Levomethylfolate focused on providing a stable, bioavailable form of L- methylfolate. This compound was synthesized to enhance its stability and efficacy as a dietary supplement and therapeutic agent. Calcium Levomethylfolate is widely used as a dietary supplement to address folate deficiency. It is particularly important for individuals who have difficulty converting folate to its active form due to genetic variations or health conditions. As a supplement, it supports various physiological functions, including cell division and the production of red blood cells. During pregnancy, adequate folate intake is essential for fetal development, especially in preventing neural tube defects. Levomethylfolate calcium is used in prenatal vitamins to ensure pregnant women receive adequate levels of active folate, which is essential for healthy fetal growth and development. Research suggests that levomethylfolate calcium may have potential benefits for mental health. It is being studied for its role in treating mood disorders such as depression, especially in individuals with genetic mutations that affect folate metabolism. The compound's ability to cross the blood-brain barrier and affect neurotransmitter function makes it a hot topic in psychiatric research. Elevated homocysteine ​​levels are associated with cardiovascular disease. Levomethylfolate calcium may help regulate homocysteine ​​levels by supporting its metabolism. This application is beneficial for individuals who have elevated homocysteine ​​levels and may not be able to metabolize folate effectively. Brand: Soarwin CAS No.: 151533-22-1 EC Number: 691-636-3 Molecular Formula: C20H23CaN7O6 Melting point: >300°C(lit.)

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liquid crystal monomer 3PCH 61203-99-4 Established in 2007, Qingdao QY Liquid Crystal Co., Ltd is a leading manufacturer specializing in high-quality nematic liquid crystals, primarily used in PDLC smart film and high grade of LC display. With over 18 years of nematic liquid crystals production expertise. Our LCs are widely exported to Europe, the United States, South Korea, and other global markets. The capable of our producing approximately 5000 kilograms per month. We signed the Exclusive Agency Agreement with our South Korean customer from 2011

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2-Methylthio-4-pyrimidinol is a competitive inhibitor of Nitric Oxide Synthase (NOS) and is used in various chemical and pharmaceutical applications. It is also an intermediate in the synthesis of certain pharmaceuticals. Brand: Soarwin CAS No.: 5751-20-2 EC Number: 227-274-6 Molecular Formula: C5H6N2OS Density: 1.35±0.1 g/cm3 Boiling point: 301.2 °C at 760 mmHg Melting point: 200.0 - 204.0 °C Flash point: 136 °C

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Trans-1,2-cyclohexanediamine is a cyclic aminocarbon compound, which is often used in the synthesis of organic functional small molecules such as chiral ligands or chiral stationary phases. As a chiral amine compound, it can also be used as a chiral catalyst in organic chemical reactions. It can also be used for the synthesis of polydentate ligands, chiral substances and chiral stationary phases.. Brand: Soarwin CAS No.: 1121-22-8 EC Number: 601-163-6 Molecular Formula: C6H14N2 Density: 0.951 Melting point: 14-15°C Boiling point: 79-81 °C Flash point: 68 °C

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7-Dehydrocholesterol is separated and extracted from pig skin. It can also be obtained by acylation, oxidation, hydrazone, dehydrazone and saponification of cholesterol. It is a pharmaceutical intermediate synthesized by saponification reaction of 7-dehydrocholesterol. Brand: Soarwin CAS No.:434-16-2 EC Number:207-100-5 Molecular Formula:C27H44O Density:0.9717 (rough estimate) Melting point:148-152 °C(lit.) Boiling point:451.27°C (rough estimate) Flash point:212.3oC

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Cholesterol, also known as cholesterol, is a derivative of cyclopentane polyhydrophenanthrene. It is an important component of various membrane structures of human cells and nerve myelin sheaths. It is widely present in animals, especially in the brain and nerve tissues. It is also found in high levels in the kidneys, spleen, skin, liver and bile. Its solubility is similar to that of fat. It is insoluble in water but easily soluble in solvents such as ether and chloroform. Brand: Soarwin CAS No.:57-88-5 EC Number:200-353-2 Molecular FormulaC27H46O Density:1.06 Melting point:148-150 °C Boiling point:360 °C Flash point:250 °C

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