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Since Gadopentetate Dimeglumine Injection was launched in 1992 by Beilu Pharma in China, it was highly recommended and accepted by the radiologist, and quickly occupied the market with its excellent quality and reasonable price. Up to now, linear gadolinium has been safely used for nearly 30 years, with excellent enhancement effects and few side effects. Product name: Gadopentetate Dimeglumine Injection Generic name: Gadopentetate Dimeglumine Injection Type: Injectable Contrast Media for MRI, Linear Contrast Media No.1 market share in China Ingredients: Gadopentetate Dimeglumine Specification: 10ml:4.69 g; 12ml:5.63 g; 15ml:7.04 g; 20ml:9.38 g Posology and method of administration: Intravenous injection Adverse reactions: See the details from the package insert Shelf life: 36 months Indication of Gadopentetate Dimegumine Injection Magnetic resonance imaging of the central nervous system (brain and spinal cord), abdomen, chest, pelvis, limbs and other human organs and tissues. Precautions of Gadopentetate Dimegumine Injection 1. Use with caution in patients with severe kidney damage, epilepsy, hypotension, asthma and other allergic respiratory diseases and those with allergic tendencies. 2. Take care to avoid the extravasation of the gadopentetic acid liquid during injection to prevent tissue pain. 3. The serum iron and bilirubin levels of some patients will increase slightly after medication, but they are asymptomatic and can return to normal within 24 hours. 4. Pregnant women and breastfeeding women should use it with caution. Animal experiments show that a small amount of medicine liquid enters the milk. 5. The effective enhancement time of Magnevist contrast is 45 minutes. MRI examination should be performed immediately after intravenous injection. 6. The remaining medicine liquid after one examination should not be used again. 7. When applying this type of MRI contrast media, follow the relevant safety regulations in magnetic resonance imaging. 8. GBCAs should be used with caution. When plain scan MRI cannot obtain the corresponding vital diagnostic information, GBCAs can be used, and the lowest approved dose is used as much as possible. 9. Gadolinium deposition Current evidence shows that after repeated use of GBCAs, trace amounts of gadolinium can remain in the brain and other body tissues. Research reports have shown that multiple uses of GBCAs can increase the intensity of brain signals, especially in the dentate nucleus and globus pallidus. Currently, there are more reports about linear GBCAs and fewer reports about macrocyclic GBCAs. Animal experiments have shown that the amount of gadolinium deposited after repeated use of linear GBCAs is higher than that of repeated use of macrocyclic. The clinical significance of brain gadolinium deposition is unclear. In order to minimize the potential risks associated with gadolinium deposition in the brain, it must be used in strict accordance with the indications and approved doses. It is recommended to use the lowest approved dose that meets the requirement of diagnosis and perform a careful benefit-risk assessment and patient informed communication before repeated administration. Bei lu is a professional contrast media manufacturing companies, we provide gadopentetate dimeglumine, mri contrast medium, contrast media products and etc. Want to know more? Please contact us.

Minimum Order: 20 square metres

The main component of CT/X-ray Contrast Media is iodine. The Iodinated Contrast Media is a colorless, transparent, slightly viscous liquid. At present, the CT contrast agents can be mainly divided into ionic and non-ionic, according to the osmotic pressure can be divided into hypertonic, isotonic and hypotonic. Currently, non-ionic, isotonic or hypotonic Contrast Media are used clinically. When the CT contrast medium is injected, 97% of the contrast media products can be directly excreted from the kidneys within 1 day. Types of Contrast Media Iohexol Injection Iohexol Injection is non-ionic contrast agent. Compared with traditional ionic contrast agent, Iohexol Injection has the excellent molecular structure, it has greatly improved safety, and significantl... Iopamidol Injection Iopamidol Injection is the second-generation non-ionic iodinated contrast media launched in the global market. In 2015, Beilu firstly launched and listed this product in the Chinese market. Product name: Iopam... Iodixanol Injection Iodixanol Injection is a Contrast Media that is isotonic with plasma. It has excellent cardiac safety and renal safety, which is most comfortable to use, especially suitable for high risk patients. Reasonable Use of Iodinated Contrast Agents Evaluate patient benefits/risks before use History of allergies: Patients who have previously experienced moderate to severe anaphylactoid reactions to iodinated contrast agents or patients with a history of allergies requiring treatment are at an increased risk of having an allergic reaction to CT scan contrast dye. Kidney function: iodinated contrast agents can cause acute kidney injury, and patients should be evaluated for related risks before the surgery. Combination medication: drugs that may increase the risk of adverse reactions to iodinated contrast agents: neuroleptics and antidepressants, interleukin-2, beta-blockers, metformin. Situations where iodinated contrast agents should be used with caution: lung and heart diseases, catecholamine secreting tumours, pregnant and lactating women, myeloma and macroglobulinemia, myasthenia gravis, homocystinuria. Contraindication: uncured patients with hyperthyroidism. Dose limit for iodinated contrast agents On the premise of satisfying imaging/diagnosis, the minimum dose of iodinated contrast agents should be used. For low-risk patients, the total dose of types of contrast agents had better be controlled within 300 ~ 400 ml. Maximum dose of iodinated radiocontrast dye Method I *: 5 ml × body weight (kg)/serum creatinine (mg/dl) (not more than 300 ml) [refer to Cigarroa calculation formula] Method II: 3.7 times creatinine clearance [according to 2011 ACCF/AHAUA/NSTEMI Treatment Guidelines] For those with severe renal insufficiency, try to choose an imaging method that does not require iodine-based contrast agents or a non-imaging method that can provide sufficient diagnostic information. Avoid repeated use of the diagnostic dose of an iodinated contrast medium in a short period of time. If repeated use is indeed necessary, it is recommended that the interval between two MRI contrast agent applications be ≥14 days. Other precautions for the use of iodinated contrast agents Preheating: Before using an iodinated contrast agent, it is recommended to heat the contrast agent to 37 °C and place it in a thermostat. Hydration: It is recommended to hydrate patients within 6 to 12 hours before using an iodinated contrast agent to within 24 hours after use. Hydration method: Intra-arterial drug users are advised to receive intravenous rehydration and oral rehydration concomitantly, and oral rehydration is recommended for intravenous drug users. Stay and observation: After the injection of the iodine-based contrast media, the patient needs to stay and be observed for 30 minutes before leaving the examination room. Establish an emergency channel: Establish an emergency rapid support mechanism for the rescue of adverse reactions caused by iodinated contrast agents with the emergency room or other clinical related departments to ensure that after an adverse reaction occurs, clinicians can promptly rush to the rescue scene for rescue if necessary. Prevention and Management of Vascular Extravasation of Iodinated Contrast Agents Prevention Choose appropriate blood vessels for venipuncture and operate carefully; when using a high-pressure syringe, choose a puncture needle and catheter that match the injection flow rate; properly fix the puncture needle; communicate with the patient and get cooperation. Management Mild extravasation: Most injuries are minor and need no treatment. However, the patient should be instructed to keep observing. If the extravasation worsens, the patient should seek medical attention in time. For individuals with significant pain, common cold and hydropathic compresses can be given locally. Moderate and severe extravasation: ① raise the affected limb to promote blood return. ② Use 50% magnesium sulfate moisturizing cold compress in the beginning, and after 24-hours change to magnesium sulfate moisturizing hot compress, or use mucopolysaccharide ointment for topical application, or use 0.05% dexamethasone for local hydropathic compress. ③ Those with severe contrast agent extravasation should be given oral dexamethasone 5 mg/time tid for 3 consecutive days on the basis of topical drug use. ④ If necessary, consult a clinician for medication. Bei lu is a professional contrast media manufacturing companies, we provide ct contrast agent, mri contrast medium, contrast media products and etc. Want to know more? Please contact us.

Minimum Order: 20 square metres

For the purpose of medical imaging, a certain substance is introduced into the human body to change the image contrast of local tissues of the body. This introduced substance is Contrast Media, also known as Contrast Agents. As the first Contrast Media manufacturer in China, Beilu Pharma launched the domestic MRI Contrast Media Gadopentetate Dimeglumine Injection in 1992, which broke the foreign products monopoly and filled the domestic gap. As a well-known contrast media manufacturing companies, we could provide a broad portfolio stems Contrast Media across CT/X-ray and MRI modalities, and own the EU standard manufacturing facilities. Types of Contrast Media in Beilu Pharma Magnetic Resonance Imaging (MRI)Contrast Media is Gadolinium based contrast agent(GBCA). It is an intravenous injection, mainly used to enhance the image quality of internal organs, blood vessels and tissues during MRI examinations. GBCA contains gadolinium, which is connected to each other through carrier molecules to form a chelating agent. According to the different chemical structures, this contrast medium can be divided into two categories: linear and macrocyclic. The linear structure of the imaging agents is easier to release gadolinium ions, and the macrocyclic structure of the contrast material is more stable and less likely to release gadolinium ions. CT/X-RAY CONTRAST MEDIA Iodine-containing Contrast Media is one of the common imaging contrast agents used in radiology diagnosis and interventional therapy. It is also a basic diagnosis drug for cardiovascular imaging under X-ray. Currently, the iodinated Contrast Media used for cardiovascular system CT and digital subtraction angiography are all water-soluble organic iodinated contrast materials. Finished Types of Contrast Media S. No Product name Characteristic Specification 1 Gadopentetate Dimeglumine Injection Injectable solution 469mg/ml:  10ml, 12ml, 15ml, 20ml 2 Gadobutrol Injection Injectable solution 604.72mg/ml:  7.5ml 3 Ammonium iron citrate Oral granules 3g：0.6g（Fe 129mg） 6g：1.2g（Fe 258mg） 4 Iopamidol Injection Injectable solution 300mgI/ml:  50ml, 100ml 370mgI/ml:  50ml, 100ml 5 Iodixanol Injection Injectable solution 270mgI/ml:  100ml 320mgI/ml:  50ml, 100ml 6 Iohexol Injection Injectable solution 300mgI/ml:  20ml,50ml,75ml, 100ml 350mgI/ml:  20ml, 50ml, 100ml API & Intermediates Types of Contrast Media S. No Products CAS NO. Packings Classification 1 Iohexol 66108-95-0 25kg Contrast agent 2 Iodixanol 92339-11-2 25kg Contrast agent 3 Iopromide  73334-07-3 25kg Contrast agent 4 Iopamidol 60166-93-0 25kg Contrast agent 5 Ioversol 87771-40-2 25kg Contrast agent 6 Gadopentetate Monomeglumine 92923-57-4 25kg Contrast agent 7 Gadopentetate Dimeglumine 86050-77-3 25kg Contrast agent 8 Gadobutrol 138071-82-6 25kg Contrast agent 9 Calcobutrol 151878-23-8 2kg Excipients 10 Repaglinide 135062-02-1 10kg Anti-diabetic 11 Diethylenetriaminepentaacetic acid ( Pentaacetic Acid)（DTPA） 67-43-6 2.5kg Intermediates 12 Iopamidol Intermediate (order based) 5-Amino-2,4,6-triiodoisophthalic acid 35453-19-1 25kg Intermediates Comparison of physicochemical characteristics of commonly used Contrast Media Contrast media (Concentration：mg（I）/ml) Osmotic pressure (mOsm/kg water） Viscosity （cP，37℃） Iopamidol 300 616 4.7 Ioverol 300 651 5.5 Iohexol 300 672 6.3 Iobitridol 300 695 6 Iodixanol 320 290 11.8 The osmotic pressure of normal people is about 290-300mOsm/kg. Taking the viscosity of water as 1, when the temperature is 37℃, the relative viscosity of whole blood is 4-5, and the relative viscosity of plasma is 1.6- 2.4. Three factors of renal injury induced by Contrast Media: Osmotic pressure, Viscosity and the total iodine. Reduced iodine intake is a feasible strategy to avoid kidney damage. Beilu is a professional contrast media companies, we provide ct contrast agent, mri contrast medium, contrast media products and etc. Want to know more? Please contact us.

Minimum Order: 20 square metres

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Minimum order quantity 100g Price Negotiable Lead time Within 3days upon receipt of payment Delivery time About 3 days Packaging details Aluminum foil bags or fiber drum Trade terms CIF,CFR, FOB Payment terms T/T,West Union,Paypal, Credit Card Port Shanghai Port,Guangzhou Port,Tianjin Port Our advantages 1.High quality with competitive price. 2. All purity>99%. 3. We are manufacturer and can provide high quality products with factory price. Fast and safe delivery. 1. Parcel can be sent out in 24 hours after payment tracking number available. 2. Secure and discreet shipment verious transportation methods for your choice. 3. Customs pass rate >99%. 4. We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

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Items Specifications Product Name 2-Oxiranecarboxylicacid, 3-(1,3-benzodioxol-5-yl)-2-Methyl-, ethyl ester CAS Number 28578-16-7 Molecular Formular C13H14O5 Molecular Weight 250.25 Boiling Point 327.8±42.0 °C(Predicted) Density 1.302±0.06 g/cm3(Predicted) Our Service: 1. Best quality in your requirement 2. Competitive price in china market 3. Mature technical support 4. Professional logistic support 5 . Full experience of large numberscontainers loading in chinese sea port 6 .Fast shipment by reputed shipping line 7. Packing with pallet as buyer's special request 8. Best service after shipment. 9. Cargoes together with container after-sales service available 10. Full experience in export 11. Raw materials from chinese origin

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PRODUCT DESCRIPTION Tilmicosin 30% Injection Veterinary Medicine Drugs For Sheep Cattle Swine Poultry Description of Tilmicosin injection 30% : Tilmicosin is a broad-spectrum semi-synthetic bactericidal macrolide antibiotic synthesized from tylosin. It has an antibacterial spectrum that is predominantly effective against Mycoplasma, Pasteurella and Haemophilus spp. and various Gram- positive organisms such as Corynebacterium spp. It is believed to affect bacterial protein synthesis through binding to 50S ribosomal subunits. Cross-resistance between tilmicosin and other macrolide antibiotics has been observed. Following oral administration, tilmicosin is excreted mainly via the bile into the faeces, with a small proportion being excreted via the urine. Indication of Tilmicosin injection 30% : For first-line control and treatment of Bovine Respiratory Disease (BRD). Also used for the treatment of respiratory bacterial diseases in large ruminants, caused by Pasteurella miltocida, Mannheimia (Pasteurella) haemolytica, infection processes associated with Haemophilus somnus, Histophilus spp. etc. Contra indications of Tilmicosin injection 30% : Hypersensitivity or resistance to tilmicosin. Concurrent administration of other macrolides or lincosamides. Administration to animals with an active microbial digestion or to equine or caprine species. Parenteral administration, especially in porcine species. Administration to poultry producing eggs for human consumption or to animals intended for breeding purposes. During pregnancy and lactation, use only after a risk/benefit assessment by a veterinarian.

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