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The detection kit, which is based on the BES 4000 platform, is used to perform low-depth whole-genome sequencing of DNA. The sequencing results are compared to the base sequence of the human reference genome, and CNVs in the tested samples are discovered using bioinformatics analysis. It is often used to find out why a woman keeps having miscarriages, find out what is wrong with an abnormal fetus, and help with a prenatal diagnosis. As one of the most professional ivd diagnostics companies, we provide cnv detection software, ngs cnv detection, cnv ngs, cnv detection, life sciences instruments, dna sequencing service, etc. For more information, please feel free to contact us!

The cma practice test of CapitalBio Technology uses Affymetrix GeneChip System 3000Dx and CytoScan 750K chip, it can not only provide accurate detection of chromosomal gene abnormalities, and provide an effective diagnostic basis for clinical birth defects, but also provide corresponding value-added services of prenatal data analysis and report interpretation, which is more convenient for clinicians' daily diagnosis and practical application. Features of CMA Detection ThermoFisher Affymetrix GeneChip System 3000Dx (GCS 3000Dx) chip system provides accurate and rapid birth defect diagnosis services. It is the most reliable platform for clinical research and the only chip system approved by the US FDA and China CFDA with EU IVD and CE marks, suitable for RNA and DNA- based clinical detection. Product Coverage of CMA Detection Prenatal detection and diagnosis of chromosomal abnormalities Sample types: Peripheral blood, villi, amniotic fluid, cord blood and abortus It can detect various chromosomal fetal chromosomal abnormalities, including copy number variation (CNV), uniparental diploidy (UPD), loss of heterozygosity (LOH), mosaicism, etc., such as Fancomi anemia or VACTERL syndrome caused by CNV; UPD caused Angelman syndrome, Prader Willi syndrome; and chromosomal abnormalities such as Autism, Cri-du-chat syndrome, Wolf Hirschhorn syndrome, Williams Beuren syndrome, etc. Neonatal genetic disease diagnosis Sample type: Peripheral Blood Precise genetic diagnosis of children with birth defects such as mental retardation, developmental delay, polymorphism, autism, ADHD, epilepsy, neuromuscular disorders, and congenital heart disease Specification of CMA Detection CNV probe 550,000 SNP probe 200,436  Resolution 100kb LOH/UPD ＞5MB For more information about transcriptome sequencing service and in vitro diagnostic assay, please feel free to contact us!

At present, there are more than 20,000 human genes have been discovered, with a total of more than 180,000 exons. Genes are composed of exons and introns, where exons are DNA regions directly involved in protein coding, accounting for about 1-2% of the entire human genome, and about 85% of human genetic variation is concentrated in the exon region. Therefore, whole exome sequencing genetic test can provide comprehensive and powerful information for the diagnosis of diseases. Features of Clinical WES The Clinical WES test of CapitalBio Technology is based on the BES4000 semiconductor sequencing platform, uses target region capture and the NGS technology to detect all exonic regions and more than 1,000 pathogenic intron regions of nearly 4,000 genes that are clearly associated with genetic diseases, covering more than 4,200 diseases. Disease Category Number of Diseases Number of Genes Nervous system 793 688 Genetic metabolic system 631 570 Genitourinary 102 97 Hereditary eye disease 359 299 Skeletal system 596 466 Respiratory diseases 42 57 Mental and behavioral disorders 128 128 Endocrine System 217 231 Skin system 253 212 Hearing disease 124 107 Digestive system 72 72 Blood immunity 426 425 Circulatory system 223 177 Tumor 142 185 Others 161 163 Applications of Clinical WES Auxiliary diagnosis: patients with suspected single-gene genetic disease. Fertility guidance: couples who have family history or have given birth to sick children. Risk assessment: high-risk groups with family history. Advantages of Clinical WES High accuracy: Average sequencing depth > 200X, 30X coverage of target area > 95%. Fast: 20 working days to deliver report. Specification of Clinical WES Sample Types Requirements Whole blood [EDTA tube] Adults ≥ 5mL, children ≥ 2mL DNA Concentration > 30ng/uL, total amount > 1ug, 40uL Tissue 0.5 X 0.5 cm For more information about genome sequencing service and in vitro diagnostic solutions, please feel free to contact us!

Centrifugal heat sealing machine has chip centrifugation and chip heat sealing functions that can be used simultaneously without interfering with each other. The shell, heat sealing module, centrifugal module, control unit, and touch screen comprise the centrifugal heat sealing machine. It is suitable for centrifugal injection and heat sealing blocking after SNP chip injection, so that the SNP chip forms an independent reaction chamber. Prevent inter-sample interference. Features of Centrifugal Heat Sealing Machine The heat-sealing process can be performed on four chips simultaneously. Display on a sizable screen, easily adjustable settings Thermostats utilizing digital PID technology provide precise temperature regulation. Completely enclosed, dependable operation Cross-contamination is prevented owing to the reaction chambers' isolation from one another. Specification of Centrifugal Heat Sealing Machine Chip size (75±0.50)mm×(25±0.25)mm×(2.00±0.10)mm Proc , essing throughput 250 chips/hour Temperature range 150~180 ℃ Temperature Precision ±1℃ Blocking time 1~99s Capacity 2,4 microfluidic chips Working speed 8000rpm single centrifugation time 1 min Dimension (L×W×H) 470mm×345mm×400mm Weight 45kg As a professional microarray company, we provide whole mitochondrial genome analysis, life sciences instruments, genome sequencing service, etc. For more information, please feel free to contact us!

The CapitalBio® SlideWasher cleans and spin-dries DNA and protein microarray slides after labeling reactions. It integrates and automates slide cleaning at the same time, significantly improving the reproducibility of microarray scanning results. Features of CapitalBio® Slide Washer Accurate temperature control helps optimize washing conditions Integration of slide washing and centrifuge functions in one unit The timer ranges from 0 to 60 minutes Small footprint Specification of CapitalBio® Slide Washer Chip size (76.20±0.50)mm×(25.40±0.25)mm×(1.00±0.10)mm Capacity 24 slides Temperature range RT~60 ℃ Washing speed 100/150/200/250/300 rpm, 10 options Washing buffer consumption 400ml/cycle Line Voltage 110-220 VAC Line Frequency 50-60HZ Dimension (W×D×H) 560mm×530mm×365mm Weight 35kg There are many ivd diagnostics companies, but we are one of the best choices for you.

CapitalBio® Microarray Scanner LuxScan™10K/D, a novel optical system design based on the laser confocal principle, improves detection sensitivity and is suitable for dual-color or single-color fluorescence detection and analysis of high, medium, and low-density biochips. The LuxScan™10K/D optical system works on the laser confocal principle. It increases the sensitivity of detection and can be used for either single-color or dual-color fluorescence detection and analysis of high, medium, or low density biochips. Features of CapitalBio® Microarray Scanner LuxScan™10K/D The first microfluidic in situ fluorescence scanner for detecting amplified nucleic acids Two fluorescence detection channels can be monitored independently due to sequential scanning, and the laser intensity and PMT can be fine-tuned in real- time. LuxScan10K/D has a much larger numerical aperture of 0.76 than the industry standard of 0.68. The amount of light that can be collected is directly related to the lens's numerical aperture. Specification of CapitalBio® Microarray Scanner LuxScan™10K/D Chip size Length (74.85~75.00)mm/ Width(24.85~25.00)mm/Thickness(1.900~2.000)mm< , br>Scan zone ≥22×72mm, equipped with a customized scanning zone Scanner resolution Options include 5um, 10um, 20um, and 40um resolutions. Scan speed ≤30s/cm2 (10um resolution) Sensitivity ≤0.1 fluorescent molecules/um2 Repeatability ≥95%, CV≤10% Weight ≤40kg Dimension (L×W×D) 540mm×360mm×220mm As one of the most professional biotech sequencing companies, we provide genechip scanner, sequencing solutions, etc. For microarray scanner price or more information, please feel free to contact us!

The CapitalBio LuxScan™ 10K dna microarray scanner is a compact high performance system for microarray imaging and the analysis of DNA, protein, and cell arrays. Its advanced systems for optics, signal processing, and motion control provide superior scan accuracy and high detection sensitivity over a wide linear dynamic range. With the optimized signal acquisition and processing elements, it is ideal for profiling high-density spotted microarrays. LuxScan™ 10K-A has two excitation lasers (532nm and 635nm) and scans sequentially, avoiding potential signal crosstalk for dual labeled arrays. LuxScan™ 10K-B comes with either a 532nm or 635nm excitation laser. It has a National Registration Certificate for Medical Devices and is suitable for diagnostic uses. Features And Advantages Of CapitalBio® Microarray Scanner LuxScan™10K Proprietary confocal optical design Sequential scanning, without cross-talk between channels High resolution and high sensitivity Laser intensity and PMT are continuously adjustable Flexibility in dye selection Image quality & signal to noise ratio (SNR) superior to equivalent instruments Remarkably compact, the bench-top footprint of 54 cm × 36 cm Easy-to-use, powerful integrated acquisition, and analysis software - SpotData™ Pro 3.0 with three licenses for each instrument, and free upgrades for the first 5 years LuxScans are available in U.S. standard and European slide formats LuxScan™ 10K Autofocus software allows users easily readjust the altered focus due to rough shipment and for its long term maintenance Specification Of CapitalBio® microarray reader LuxScan™10K Features Parameters cnip Formats: Standard USA Slides (76.2士0.5)×(25.4土0.25)× (1.0土o.1) mm or European slides versions (76.2士0.5)×(25.6土0.25)×(1.0土o.i1) mm Maximum Scan Area 22 mm x 72 mm Excitation wavelength 532 nm and/or 635 nm Emission wavelength 570土10 nm,675土10 nm (expandable to 6 types) Applicable Fluorescence Dyes cy3.cy5, etc. scan Resolution user-selectable: 5,10,20,40 um sensitivity 0.1 chromophores / um2(cpsm)(cy3) scan speed 8 mins / chip (10 um resolution) Dynamic Range 104(16 bit) Repeatability 95% Laser Power settings 5-100 % continuously adjustable PMT Adjustment 450-950 continuously adjustable Focus Distance 土250 um lmage File Format TIFF.BMP, JPG, RAW voltage Ac l1o v/Ac 220v Power 75 watts size (w x D*H) 360 mm x 540 mm x 220 mm (14.2 in x 21.3 in x 8.7 in) weight 40 kg (88 lb) As one of the most professional biotech genetic sequencing companies, we provide protein chip, life sciences instruments, etc. For more information, please feel free to contact us!

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