Cosmetic & Hair Care Chemicals

INCI Name: Tripeptide-3 Reference: AT Peptide IS Formula: C14H24N8O4 Molecular: 368 Purity: ≧95% Stability: stable Odor: no Grade: cosmetic Source: synthetic Formulation: available for your reference, please contact us. COA and MSDS: available for your reference, please contact us. Delivery: promptly from stock Concentration additive: 1.5 PPM Capacity: 5kg per month Appearance: white powder 2.Functions: 1.Increases ATP levels 2.Increases intracellular calcium 3.Helps lipolysis 3.Introduction: Tripeptide-3 is an energy-boosting peptide specially designed to help revitalize aging skin as well as help smooth the appearance of cellulite prone skin

INCI Name::AHK, Tripeptide-3 Cas No: 89030-95-5, 49557-75-7,130120-57-9 Formula: C15H26N6O4( AHK) Molecular: 353.0(AHK) Sequence: AHK Purity: ≧95% Solubility: slightly soluble in water Stability: stable Odor: no Grade: cosmetic Source: synthetic Formulation: available for your reference, please contact us. COA and MSDS: available for your reference, please contact us. Delivery: promptly from stock Capacity: 10kg per month Appearance: white powder 2.Functions：Tripeptide-3 effectively increase collagen and elastin production. It prevent hair loss, improve hair growth and supply nutrients for hair.

INCI Name: Trifluoroacetyl Tripeptide-2 Synonym: ECM-Protect, Progeline Cas No: 64577-63-5 Formula: C21H28F3N3O6 Molecular:475.47 Solubility: s , lightly soluble in water Stability: stable Odor: no Grade: cosmetic Source: synthetic Formulation: available for your reference, please contact us. COA and MSDS: available for your reference, please contact us. Delivery: promptly from stock Appearance: white powder 2.Usage: Trifluoroacetyl Tripeptide-2 reduces progerin synthesis, MMP and elastase inhibitor, increases syndecan, contracts collagen to reduce signs of aging including sagging and wrinkles Description: Trifluoroacetyl Tripeptide-2 is a 3 amino acids peptide biomimetic of elafin that modulates progerin, a new senescence marker, for a complete remodelling effect and reduction of the appearance of wrinkles. 3.Description: Trifluoroacetyl Tripeptide-2 Reduces progerin synthesis, MMP and elastase inhibitor, increases syndecan, contracts collagen to reduce signs of aging including sagging and wrinkles 4. Mechanism: 1. Tripeptide-2 Reduces progerin to a young cell level to delay cell senescence. 2. Tripeptide-2 Stimulates sirtuin production and activity to extend cell lifespan. 3. Tripeptide-2 Boosts collagen production and inhibits degradation enzymes activity(collagenase,elastase,MMP-1,MMP-3,MMP- , 9).

INCI Name: Copper Tripeptide-1(GHK-Cu) Cas No: 89030-95-5, 49557-75-7,130120-57-9 Formula: C14H24N6O4 Molecular: 340.5 Sequence: (Gly-His-Lys)2.Cu.Hac Purity: ≧95% Solubility: soluble in water Stability: stable Source: synthetic Odor: slightly Formulation: available for your reference MSDS and COA: available for your reference Delivery: promptly from stock Capacity: 10kg per month Appearance: Blue powder 2.Usage：Copper Tripeptide-1 can be used for anti-wrinkle,hair regrowth,wound repair, skin remodeling 3.Description: Copper is an important trace element that has been found to be important in wound healing and enzymatic processes.Lysyloxidase is an important enzyme in collagen and elastin production and it is dependent upon the action of copper. Tyrosinase and cytochrome c oxidase require copper as well.The detrimental effects of free radicals on the skin have been elucidated in basic science research into skin photoaging. Superoxide dismutase acts as an important antioxidant and requires copper as a cofactor. The peptide GHK spontaneously complexes with copper and facilitates the uptake of copper by cells. This peptide sequence is found in proteins of the extracellular matrix such as the αchain of collagen, and it is believed to be released during wounding and inflammation. A feedback stimulation of collagen repair has also been proposed for this peptide, but the main benefit to photoaged skin is believed to be the enhanced delivery of copper. Copper Tripeptide-1.

INCI Name: IAMIN Cas No: 32999-80-7 Formula: C10H15N5O4 Molecular:269.26 Sequence: Cu-HGG Purity: ≧95% MSDS and COA: available for your reference, please contact us. Delivery: promptly from stock Source: synthetic Stability: Stable Grade: cosmetic Capacity: 3kg per month Appearance: blue powder

Name: Collagen Tripeptide Cas No: 2239-67-0 Formula: C12H19N3O5 Molecular:285.3 Purity: ≧95% MSDS and COA: available for your reference, please contact us. Delivery: promptly from stock Source: botanical Stability: Stable Grade: cosmetic Capacity: 800g per month Appearance: light yellow or almost white powder  2.Usage：anti-photo-aging agent 3.Descriptiom: Collagen tripeptide (CTP) is a functional food material with several biological effects such as improving dry skin and wound and bone fracture healing. Collagen molecule consists of 3,000 amino acids, can hardly be absorbed by human gastrointestinal use, not to direct absorption by the skin. Tripeptide collagen is 3,000 amino acids according to 1 / 1000 of shearing, forming a function of the smallest molecular structure of collagen, or a combination of three amino acids. Tripeptide collagen collagen than usual excellent with more absorbent, can penetrate the dermis, and bring better effect of moisture. And collagen III peptide itself has anti-inflammatory and regenerative capacity of the cell has, so you can remove facial pock metabolism to generate healthy skin.

INCI Name: Pal-AHK Cas No: 147732-56-7 Formula: C31H56N6O5 Molecular:592.8 Sequence: Pal-AHK Purity: ≧95% MSDS and COA: available for your reference, please contact us. Delivery: promptly from stock Source: synthetic Stability: Stable Odor: no Grade: cosmetic Capacity: 2kg per month Appearance: white powder Functions: Palmitoyl Tripeptide (Pal-AHK) effectively increase collagen and elastin production. It prevent hair loss, promote wound healing improve hair growth and supply nutrients for hair growth.

INCI Name:Palmitoyl Tripeptide-1(Palmitoyl Oligopeptide) Reference: DermaPep A310,Bio-bustyl, Corum 8803 / 8813 / 8813CC,Maxilip Cas No: 147732-56-7 Formula: C30H54N6O5 Molecular:578.8 Sequence: Pal-GHK Activity: Stimulate collagen and glycosaminoglycan synthesis Purity: ≧95% Source: synthetic Stability: Stable Grade: cosmetic MSDS and COA: available for your reference Delivery: promptly from stock Capacity: 1kg per month Appearance: white powder 2.Usage：Anti-wrinkle and firming effect. 3.Description: This peptide sequence is found in proteins of the extracellular matrix such as the αchain of collagen, and it is believed to be released during wounding and inflammation. A feedback stimulation of collagen repair has also been proposed for this peptide, but the main benefit to photoaged skin is believed to be the enhanced delivery of copper.It is found to have the beneficial effects on collagen stimulation. Palmitoyl Tripeptide-1 is a matrikine, it stimulates collagen and glycosaminoglycan synthesis. Palmitoyl Tripeptide-1 reinforces the epidermis and diminishes wrinkles.

INCI Name: Biotinoyl Tripeptide-1 Reference: Procapil,widelash Cas No: 299157-54-3 Formula: C24H38N8O6S Molecular:566.67 Sequence: Biotin-Gly-His-Lys-OH Solubility: soluble in water. Source: synthetic Stability: stable,intolerance to strong alkalis Purity: ≧95% Grade: cosmetic MSDS and COA: available for your reference Delivery: promptly from stock Capacity: 500g per month Appearance: white powder 2.Usage: eyelash, brow and hair growth 3.Description: Myristol Pentapeptide-17, Acetyl Tetrapeptide-3 and Biotinoyl Tripeptide-1 can have positive effects on the hair follicle helping scalp micro-circulation, follicle atrophy caused by dihydrotestosterone, and follicle aging.

Name: Lipospondin Formula: C21H35N5O4 Molecular:685 Sequence: N-Elaidoyl-KFK Purity: ≧95% Grade: cosmetic Source: synthetic Stability: stable Appearance: white powder MSDS and COA: available for your reference Delivery: promptly from stock 2.Usage: prevent age-associated dermal alterations防止年龄相关的皮肤改变 3. , Description：N-Elaidoyl-KFK as well as KFK were shown to activate LAP-TGF- beta both in vitro, using a solid phase assay with immobilized LAP-TGF-beta, and ex vivo using human dermal fibroblasts cultures. In both assays, as much as up to 10% of LAP-TGF-beta added could be recovered as active form. KQK, KQFK as well as their lipopeptide counterparts were inactive. Elaidyl-KFK- mediated LAP-TGF-beta activation led to up-regulation of collagen and TIMP-1 production and down regulation of PMA-induced MMP-1 expression in fibroblasts cultures. Those effects could be suppressed by supplementing cell culture medium with blocking TGF-beta antibody. Elaidyl-KFK inhibited MMP-2, MMP-9, MMP-3, MMP-1, in vitro with IC(50) equal to 1.2, 1.0, 0.24 and 8.9 microM, respectively. Its ex vivo inhibitory capacity, as assessed using skin tissue sections, towards the elastin-degrading capacity of MMP-9 was even more pronounced. At a 1 microM concentration, the lipopeptide decreased by up to 80% enzyme activity. Thus, "Lipospondin," i.e. elaidyl-KFK might be considered as a promising model compound to prevent age-associated dermal alterations.

INCI Name:Tripeptide-1 Reference: Aldenine, Liporeductyl, Kollaren,Hilurlip, Prezatide, Liver cell growth factor Cas No: 72957-37-0 EINECS number: 277-125-4 Formula: C14H24N6O4 Molecular:340.5 Sequence: GHK Purity: >95% Grade: cosmetic Source: synthetic Odor: no Stability: stable Formulation: available for your reference Delivery: promptly from stock Capacity: 5kg per month Recommended use level: 1 - 10%. Appearance: white powder 2.Functions: Tripeptide-1 Increases skin firmness, Improves tissue renewal & healing 3.Introduction：Tripeptide-1 possesses a high affinity for copper(II) ions, with which it spontaneously forms a complex (GHK-Cu). This growth-modulating plasma tripeptide, when added at nanomolar concentrations to a wide group of cultured systems, produces a disparate set of responses ranging from the stimulation of growth and differentiation to outright toxicity. It may function by facilitating copper uptake into cells. GHK-Cu accelerates wound healing.

INCI Name:  palmitoyl lysyl-aminovaleroyl-lysine Reference: Anew Ultimate Age Repair Night Cream Formula: C33H65N5O5 Molecular: 611.90 Purity: >95% Odor: no Grade: cosmetic Source: synthetic Stability: stable Appearance: white powder Formulation: available for your reference Delivery: promptly from stock Recommended use level:  2.Functions: Palmitoyl Lysyl Aminovaleroyl Lysine in an amount effective to increase fibronectin levels in skin cells

Basic Fibroblast Growth Factor (bFGF) is a member of the FGF family of mitogenic peptides which is comprised of at least 23 proteins. FGF signaling factors play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. It was originally named bFGF based upon its chemical properties and to distinguish it from acidic fibroblast growth factor. Synonyms: FGF-2, Fibroblast Growth Factor basic (FGFb) Grade: cosmetic Source: Escherichia coli Purity: >95% by SDS-PAGE and HPLC analyses. Physical Appearance: White lyophilized powder. Endotoxin: < 1EU/ug of growth factor as determined by LAL method. AA Sequence MTMITNSSSV PGDPLESMAA GSITTLPALP EDGGSGAFPP GHFKDPKRLY CKNGGFFLRI HPDGRVDGVR EKSDPHIKLQ LQAEERGVVS IKGVCANRYL AMKEDGRLLA SKCVTDECFF FERLESNNYN TYRSRKYSSW YVALKRTGQY KLGPKTGPGQ KAILFLPMSA KS Molecular Weight: Approximately 18.5 kDa, a single non-glycosylated polypeptide chain containing 172 amino acids Biological Activity: Fully biologically active. The ED50 is < 1.0ng/ml, corresponding to a specific activity of 1.0×106 Units/mg, as determined by the proliferation of BALB/c 3T3 cells. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4, containing 4% mannitol. Reconstitution: Reconstitute in sterile distilled water containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Storage: Store at -20oC after receiving. Upon reconstitution, store at 2-8oC for up to one week. For maximal stability, aliquot and store at -20°C. Avoid repeated freeze/ thaw cycles. Usage: This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures.

Keratinocyte Growth Factor-2 (KGF-2) was originally identified from rat embryos by homology-based polymerase chain reaction. Human and mouse KGF-2 were subsequently cloned. The human KGF-2 cDNA encodes a 208 amino acid residue protein with a hydrophobic amino-terminal signal peptide. Human KGF-2 shares approximately 92% and 95% amino acid sequence identity with mouse and rat KGF-2, respectively. Among the FGF family members, KGF-2 is most closely related to FGF-7. KGF-2 transcripts has been shown to be most abundant in the embryo and adult lungs. Recombinant KGF-2 preparations have been shown to be mitogenic for epithelial and epidermal cells but not fibroblasts. Based on its in vitro biological activities and in vivo expression pattern, KGF-2 has been proposed to play unique roles in the brain, in lung development, wound healing and limb bud formation.