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Purity:98% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Retatrutide, number LY-3437943, is arguably the latest promising drug for weight loss and the treatment of type 2 diabetes in obese/overweight patients. It has a completely new mode of action, and clinical trials have shown that it is more effective in weight loss than the FDA-approved Semagelutide(Wegovy) and Tirzepatide(Mounjaro). Perhaps you have not heard of this new weight loss peptide, today we will introduce it -Retatrutide. What is peptides Retatrutide LY-3437943? For sale Retatrutide LY-3437943 basic information: Cas No.:2381089-83-2 MF:C223H343F3N46O70 MW: 4845.444 Some approved weight loss products were originally developed to treat type 2 diabetes and work based on things like appetite control and delayed gastric empting. Retatrutide, a new drug in development for the treatment of obesity, is a triple receptor agonist that activates the GLP-1(glucagon-like peptide-1) receptor,GIP(Glucose-dependent insulin stimulating) receptor and GCGR (glucagon) receptors in the body, an unprecedented way to lose weight. How does Retatrutide lose weight? A preliminary understanding of how Retatrutide works for weight loss can be found in the three receptors it acts on. GLP-1: Glucagon-like peptide 1 GLP-1 is the key word in the treatment of type 2 diabetes, which mainly plays a role in regulating blood sugar in the body. it inhibits appetite and slows stomach emptying, helping to lower blood sugar while also helping with weight loss, which is why drugs used to treat type 2 diabetes can also be used for weight loss. GIP: Glucose-dependent insulin-promoting polypeptide GIP, also known as gastric inhibitory peptides, reduces hunger and increases satiety by reducing the secretion of stomach acid and the speed at which food is transported through the stomach.

Minimum Order: 10 long tons

Peptides Melanotan-II Purity:99% HPLC Packing:10mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Product link to :www.astersteroids.com/injection-melanotan-ii-mela , notan- 2- tanning-peptide-10mg-good-price-bu , y-mt , 2-safe-shipping/ Product Name:Melanotan-II Alias : Melanotan II, 7)-lactam, Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2; CAS: 121062-08-6 Molecular formula: C50H69N15O9 MW : 1024.180 Purity : 99% Packing:10mg/vial;10vials/box Method of Analysis: HPLC Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2Ac-[Nle , 4,Asp5,D- Phe7,Lys10]alpha-MSH-(4-10)-NH2 Ap , pearance:Sterile Filtered White Lyophilized (Freeze-Dried) Storage Conditions:Aviod Shunshine and Keeping Stoppered Injection Melanotan 2 for sale benefits As a tanning peptides,Melanotan EU market is very popular during their summer holidays,usually June to Sep. Melanotan 2 10mg (also referred to as Melanotan II) is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis, a process responsible for pigmentation of the skin.Melanotan II, a originally developed as a skin tanning agent, but subsequently investigated as a potential treatment for sexual dysfunction.This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.Additionally, Melanotan 2 and a similar synthetically produced variant, known as PT-141, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.

Minimum Order: 10 long tons

Peptides HGH (Human Growth Hormone) Purity:99% HPLC Packing:10iu/vial;10vials/box.we also have 6iu to 24iu per vial for you. Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Product link to :www.astersteroids.com/injection-hgh-10iu-vial-for , -sale- good-price-with-high-quality-for-bodybui , lding/ Human Growth Sterriods Hormone Basic Info. Product Name:HGH Other Name:HGH Hormone,Human Growth HGH CAS No. : 96827-07-5 MF:C990H1529N263O299S7 Purity:abo , ve 98% Packing:HGH 10iu/vial Appearance:White Lyophilized Powder Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C. What is HGH 10iu? Human Growth Hormone,also call as HGH 10iu is not only one of the most beneficial hormones our body produces, but one of the most sought after in exogenous form. In an exogenous form, Human Growth Hormone(HGH 10iu ) is identical to the naturally produced hormone, and represents not only one of the most beneficial exogenous hormones but one of the most well-tolerated among men and women. Its high level of toleration applies not only to medicinal use but performance enhancement as well. The most common specification on the market is HGH 10iu / vial. IU is an active unit. Generally, HGH 10iu has 3.3mg. After lyophilization, it was put in an Abe bottle. Of course, we also have other specifications, such as 6iu/vial,8iu/vial,16iu/vial,24iu/vial

Minimum Order: 10 long tons

Peptides TB500 Other Name:Thymosin β4 Purity:99% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Product link to :www.astersteroids.com/injection-tb500-thymosin-be , ta-4- peptide-for-bodybuilding-to-growth-muscle , -safe-shipping-with-good-price/ Product Name:TB500 Other Name:Thymosin β4 Sequence: AC-Ser-Asp-Lys-PRO-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe , -Asp-Lys-Ser- Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-G , lu-Lys-Asn-PRO-Leu-PRO-Ser-Lys-Glu-Thr- Ile- Glu , -Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH CAS No.: 77591-33-4/107761-42-2 MF:C212H350N56O78S MW , :4963.49 Purity:above 98% Packing:2mg/vial and 5mg/vial;10vials/box Appearance:White Lyophilized Powder Method of Analysis: HPLC Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C. TB 500 Benefit:promote healing TB-500 is a synthetic fraction of the protein thymosin beta-4 peptide, which is present in virtually all human and animal cells. The main purpose of this peptide is to promote healing. It also promotes creation of new blood and muscle cells. TB 500 Benefit have been observed in tendons, ligaments, muscle, skin, heart, and the eyes. Thymosin beta-4 is naturally produced in higher concentration where tissue has been damaged. This peptide is also a very potent anti-inflamatory agent. TB 500 Benefit is an injectable peptide drug which can be used to promote healing, enhance range of motion in cases of injury, or reduce pain in case of injury by reducing inflammation.

Minimum Order: 10 long tons

Peptides Epitalon Other Name:Epithalon Purity:99% HPLC Packing:10mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Product link to :www.astersteroids.com/safe-shipping-injection-epi , talon- 10mg-peptide-for-bodybuilding-dosage-eff , ect-and-benefits/ Product Name:Epitalon CAS : 307297-39-8 Synonyms : Epitalon;Epithalon;Glycine, L-alanyl-L-a-glutamyl-L-a- aspartyl-;L-alanyl-L , -alpha-glutamyl-L-alpha-aspartylglycine; MF : C14H22N4O9 MW : 390 Appearance:Sterile Filtered White Lyophilized (Freeze-Dried) Purity:Above 98% Packing:2mg/vial;10vials/box Storage : Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C. What is Epitalon Peptide? Epitalon peptide (also known as Epithalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in humans. This pineal peptide preparation is secreted in the epithlamium- epiphyseal region of the brain. Its more prominent tasks are: to regulate metabolism in the epiphysis, increase the sensitivity of hypothalamus to its natural hormonal influences, normalize the function of the anterior pituitary, regulate the levels of gonadotropins and melatonin in the body. Epitalon peptide increases a person's resistance to emotional stress and also acts as an antioxidant. Epitalon Benefit Epitalon Benefit mianly help to Increases lifespan Boosts energy levels is also the Epitalon Benefit Improves skin appearance Helps heal injured muscle cells,this is the Epitalon Benefit for bodybuilding Promotes deeper and more restful sleep Delays or prevents age-related heart disease, cancer and dementia Tumor prevention (inhibition of cancer cells due to protective effect of elongated telomeres)

Minimum Order: 10 long tons

Peptides PT-141 Other Name:Bremelanotide Purity:99% HPLC Packing:10mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Product link to :www.astersteroids.com/hot-selling-peptide-pt-141- , bremelanotide-injection-dosage-price-to-buy/ Product Name: PT-141 Synonyms: Bremelanotide, PT-141 Acetate CAS: 189691-06-3 MF: C50H68N14O10 MW: 1025.2 Amino Acid Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH Appe , arance:Sterile Filtered White Lyophilized (Freeze-Dried) Purity:Above 98% Packing:2mg/vial;10vials/box Storage :Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C. PT-141 peptide Benefits PT-141 peptide (Bremelanotide) is a highly potent synthetic peptide analogue of α-MSH that may elicit aphrodisiac effects through stimulation of melanocortin receptors. PT-141 (Bremelanotide) consists of seven amino acids and is a cyclic, shortened lactam variant of alpha-Melanocyte-stimulating hormone (α-MSH), a multifunctional peptide that regulates a broad array of physiological functions. In studies, bremelanotide was shown to induce lordosis in an animal model and was also effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).

Minimum Order: 10 long tons

Product link to :https://www.astersteroids.com/top-quality-sarms-p , owder- lgd- 4033-with-99-purity-buy-ligandro , l-pr , ice-dosage-cas1165910-22-4/ Sarms LGD-4033 Other Name:Ligandrol Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Product Name: LGD-4033(Ligandrol) CAS: 1165910-22-4 MF:C14H12F6N2O MW:338.2482992 Appearance: white powder Purity: 99.% min Package: 10g/bag or as customers’request. Test Method: HPLC Bodybuilder knows that all testosterone replacement products, testosterone esters, etc. must have a PCT(Post Cycle Therapy) after a Cycle of use. This is because testosterone is a naturally secreted substance in the body. If exogenous supplementation is used, the body will think that the testosterone level in the body is enough and actively reduce the natural secretion of testosterone. When exogenous supplementation is stopped, the body will have low testosterone level, resulting in a series of symptoms of low testosterone. For bodybuilders, testosterone supplementation can increase muscle mass and strength, which is the original purpose for many people to start bodybuilding, so bodybuilders using testosterone supplements will be forced to choose a PCT after a normal cycle. At the same time, another group was trying to develop a class of products that had less impact on their own testosterone levels, and then succeeded in developing selective androgen receptor modulator (SARM). SARMs has tissue selective activity. They express anabolism in bone and muscle tissue and are highly selective and minimally selective in other tissues and organs. Without causing androgen side effects such as acne and prostate enlargement, SARMs became the bodybuilder’s first choice once developed. The tissue selective activity of SARMs enables some SARMs to eliminate PCT altogether, such as SR9009,MK677 and GW501516. Does SARMs LGD4033 needs PCT? It depends on the dosage. A dose-dependent increase in muscle mass was observed over 21 days in 76 adult men who received gradually increased doses of LGD4033 0.1mg,0.3mg and 1mg daily. No adverse effects were observed over 21 days. A daily dose of 1mg LGD4033 is enough to increase lean muscle mass by nearly 3 pounds. According to the survey, in bodybuilder, the dosage used is 5mg-10mg per day. For beginners, the initial dose is about 2.5g per day. A large body of data shows that when the dose is less than 5mg per day, there are few significant side effects and no need for post-cycle treatment of PCT. Some bodybuilders may be physically well tolerated, or may choose a higher dose for a given goal. If a dose of more than 10mg is used daily, between 10 and 20g, it is best to choose PCT at the end of one cycle as appropriate. Because of extensive metabolism and prolonged exposure to higher doses, there may be a large number of potential metabolites that are susceptible to haptens and secondary immune responses, resulting in certain hepatotoxicity that requires a PCT to repair. Usually, we choose Nolvadex (tamoxifen) as the PCT after the AAS cycle. LGD4033 was originally developed to increase anabolism and reduce muscle atrophy associated with catabolism and muscle mass loss. Therefore, LGD4033 is the most suitable SARMs for increasing and maintaining muscle mass, and it is usually possible to achieve this effect using very small amounts.

Minimum Order: 10 long tons

Product link to: https://www.astersteroids.com/safe-shipping , -sarms-gw501516-cardarine- powder- dosage-gw , -501 , 516-benefits-cas317318-70-0/ Sarms GW501516 Other Name:Cardarine Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Product Name: GW501516(Cardarine) CAS: 317318-70-0 MF: C21H18F3NO3S2 MW: 453.5 Appearance: white powder Purity: 99.% min Package: 10g/bag or as customers’request. Test Method: HPLC GW501516, also known as Cardarine, was first developed in 1990, 32 years ago. GW501516 was originally developed to block the growth of tumors in the colon, prostate and breast. However, when it was first introduced, it was marketed as a drug to control bad cholesterol, or low-density lipoprotein, because during early clinical trials, researchers found that it also affected blood lipid levels in humans. However, the GW501516 is really known as a bodybuilding aid. GW501516 increases metabolism and endurance. When used in bodybuilding, it helps the bodybuilder lift heavier weights or train for longer periods of time with faster recovery. It also helps burn excess body fat. It looks like a product aimed for bodybuilding. By the mid-1990s, the GW501516 was popular with bodybuilders around the world. GW501516 was subsequently introduced in 2000 as a treatment for hyperlipidemia and entered phase I trials, followed by phase II trials in 2022. Further development of GW501516 was abandoned for safety reasons in 2007, when preclinical toxicology suggested it could cause cancer. Possibly carcinogenic, because nuclear hormone activated peroxisome proliferator activated receptor β/δ (PPARβ/δ), possibly carcinogenic, not that GW501516 is directly carcinogenic. GW501516 is a peroxisome proliferator activated receptor (PPAR) agonist, which is believed to act on the nuclear hormone receptor NHR involved in glucose and lipid metabolism.GW501516 activates AMP-activated protein kinase, glucose uptake, and fatty acid oxidation in skeletal muscle. Moreover, it is controversial that PPARβ/δ activation is carcinogenic, because in the current studies on PPARβ/δ activation, it is possible that PPARβ/δ activation can both inhibit tumor production and promote tumor proliferation, which may also be related to the dose used. After all, when used for experimental purposes, High doses are often used to verify that they have optimal effects. Currently, research on activation of PPARβ/δ is still ongoing, and perhaps, in the near future, the concern will be answered. From above,we know that GW501516 is a PPAR agonist, not SARM, but because it has been classified as SARMs by bodybuilder for its similar role. Although GW501516 has a similar effect to SARMs, PPAR does not bind to androgen receptors and has no anabolic activity, so it does not affect the body’s own testosterone secretion. While it increases endurance, it does not cause difficulty falling asleep or create feelings of anxiety or tension.

Minimum Order: 10 long tons

Sarms RAD-140 Other Name:Testolone Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Product Name: RAD-140(Testolone) CAS: 1182367-47-0 Molecular formula: C20H16ClN5O2 Molecular weight:437.94026 Appearance: white powder Purity: 99.% min Package: 10g/bag or as customers’request. Test Method: HPLC Product link to :https://www.astersteroids.com/99-purity-sarms-pow , der- rad140-rad-140-testolone-good-price-for-sa , le-cas-1182367-47-0/ RAD 140 Review RAD140 is a highly effective, oral SARM (Selective Androgen Receptor Modulator) currently being studied for both anabolic and neuroprotective effects. It is in a class of androgen receptor (AR) ligands that are tissue selective, developed to treat muscle wasting associated with cancer, acute and chronic illness and age-related muscle loss. Recent research of RAD140 review shows superior lean tissue selectivity, and reduced androgenic side effects when compared to competing SARM compounds. RAD 140 powder provides is being studied for neuroprotection as well; an important neural action of endogenous androgens that is relevant to neural health and resilience to neurodegenerative diseases, and to be as effective as testosterone in reducing cell death induced by apoptotic insults. Easy to dose oral SARM that increases lean mass while remaining tissue selective in current research Added value for research with pronounced neuroprotective properties Myotrophic and neuroregeneration research compound. RAD 140 Cycle for Bulking LGD 4033 has so far shown the highest level of ability when compared to any other SARM. When you take a look at this when compared to RAD 140 cycle you will find that the two are very similar but the results you get may depend on the diet that you are on at the moment. Some users have gained over 10lbs while on the dose. RAD 140 Stack with LGD4033 If you aren’t sure how much you should be taking then you should try and take 10mg a day for 8 weeks. You can take RAD 140 cycle for longer than this according to the information that is available at the moment. If you do take LGD 4033 because you want to recomp then you’ll find that you can see a huge increase in lean muscle mass and LGD 4033 is very effective in this instance as well. RAD 140 Stack with GW 501516 If RAD 140 stack with GW-501516 then you can see even bigger results. It is not known whether LGD 4033 can be taken with RAD 140 as of yet, but if you talk to your provider then they will be able to advise you on just about anything you need and this is the best way for you to find out the information you need to know. According to results, RAD 140 cycle should be able to give you the results of LGD 4033 without any problems and this is just one of the many benefits that it can offer you. RAD 140 Stack with S4 Of course, it is entirely possible for you to use LGD 4033 to cut as well. The same concept applies to RAD 140. This is especially the case when RAD 140 stack with SARMS S4 and Cardarine, or the product mentioned above. This would be very similar to a triple RAD 140 stack and if you are doing this then try and take 5mg of either RAD 140 cycle or LGD for five weeks.

Minimum Order: 10 long tons

What are B7-33 peptides? https://www.astersteroids.com/new-peptides-b7- , 33-develop-base-on-relaxin- 2- antifibrotic- , trea , tment-of-acute-heart-failure-and-myocardial-infarc , tion/ B7-33 is a functional selective Relaxin-receptor 1 agonist in development, derived from the naturally occurring human hormone Relaxin-2. Relaxin's peptides are structurally similar to insulin-like peptides in that they consist of two chains of 53 amino acids, chain A and chain B, which are connected by three disulfide bonds to function. This chemical structure makes it difficult to recombine or chemically synthesize, so the researchers determined its minimum active structure on the basis of Relaxin and developed a single B-chain peptide analogue B7-33. The name B7-33 derives from the fact that it contains these 27 residues between 7-33 in the B-chain amino acids in Relaxin, hence the name B7-33. Use of B7-33 peptides B7-33 is the smallest active structure in Relaxin-2 and has similar effects to Relaxin, such as vascular dilation, increased renal blood flow, increased pumping volume in patients with acute heart failure without increasing cardiac burden, rapid anti-inflammatory, anti-hypertrophy, anti-fibrosis, etc. In the treatment of myocardial infarction, B7-33 induces a link between mitogen-activated protein kinase signaling and the heart's unfolded protein response after infarction, which has a protective effect against ischemia- reperfusion injury after myocardial infarction and promotes pro-inflammatory changes in the tissue during the early stages of infarct healing. B7-33 is also expected to be used in the production of anti-fibrotic materials or materials that resist foreign body reactions.

Minimum Order: 10 long tons

https://www.astersteroids.com/neuropeptide-kisspep , tin-for-sale-with-good- quanity-activation-of-g , nrh-leads-to-release-of-fsh-and-lh/ Neurope , ptide Kisspeptin Cas:1848962-29-7 MF:C63H7 , 8N18O13 · xC2HF3O2 Purity:98% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C What is Neuropeptide kisspeptin? Neuropeptide Kisspeptin, also known as kiss1, was first identified in 1996 as a transfer suppressor in human cell lines. The Kiss1 gene encodes a protein composed of 145 amino acids. In the human body, this protein is processed into a 54-amino acid peptide called kisspeptin, which, like several other neuropeptides, has a unique RF-amide motifs in its C-terminal region. It binds and activates the G-protein- coupled receptor GPR54, which stimulates hypothalamic neurons to release GnRH, leading to pituitary gonadotropin (LH and FSH) and sex hormone secretion. Kisspeptin is a key regulator of the onset of puberty, regulation of sex hormone-mediated gonadotropin secretion, and fertility control. Inactivated or activated mutations in Kiss1 and GPR54 genes are associated with hypogonadotropin hypogonadism (IHH) and precocious puberty (CPP). Neuropeptide kisspeptin has three main functions Activation of GnRH neurons in the hypothalamus leads to GnRH release, which leads to the release of FSH and LH. Inhibit the development of tumors. Treat low libido. How kisspeptin activates GnRH Neurons Bodybuilder is all too familiar with HPTA, the hypothalamic-pituitary- testicular axis whose positive and negative feedback controls the production and cessation of testosterone in men. HPGA is the hypothalamic-pituitary- gonadal axis. HPGA controls all stages of reproduction. The hypothalamus produces GnRH into the anterior pituitary and stimulates the secretion of LH and FSH. Slow GnRH pulsation is conducive to FSH secretion, while fast pulse frequency supports LH secretion. What is the hypothalamic-Pituitary-gonadal axis (HPGA)? The positive and negative feedback of the hypothalamic-pituitary-gonadal axis (HPGA) controls the secretion and cessation of sex hormones in both men and women, and its normal work maintains the normal levels of sex hormones in both men and women, thus maintaining physiological functions. This is something that happens every day in the adult body, and HPGA plays an important role in adult men and women. However, HPGA is not form in adulthood; all its components are establish in the foetus, activate in the neonatal period, then become stationary in childhood and cannot reactivate until puberty. GnRH Secretion Triggers Onset of Puberty Hypothalamic gonadotropin-releasing hormone (GnRH) neurons are functional at birth, but after a perinatal hormone surge, they are directly suppressed in infancy and no longer function. Until puberty, dormant GnRH neurons are awakened to rerelease GnRH. GnRH secreted by the hypothalamus drives the pituitary gland to secrete the release of gonadotropin (follicle-stimulating hormone FSH and luteinizing hormone LH). In males, the increased release of GnRH pulses during puberty activates gonadotropin secretion, which in turn leads to increased testosterone secretion levels in the testis, binding with FSH to initiate spermatogenesis. Tetanic LH secretion consists of intermittent episodes of hormone secretion that reflect the corresponding pattern of pulsing GnRH release in the hypothalamus. In women, increased impulsive GnRH release also drives gonadotropin secretion, which is responsible for follicular formation and estradiol (E2) secretion. After puberty is complete, HPGA is officially complete and functional. Puberty begins through increase production of GnRH, however, it remains an open question how GnRH neurons activate during puberty. Neuropeptide Kisspeptin controls GnRH pulse Production Subsequent 15 years of research have shown that hypothalamic kisspeptin acts upstream of GnRH and mediates sex hormone feedback and metabolism on the reproductive axis. This neuropeptide is necessary to start puberty and maintain normal reproductive function,

Minimum Order: 10 long tons

https://www.astersteroids.com/the-neuronootropic-p , eptide-semax-benefits- dosage-and-use-in-bodybu , ilding/ Purity:98% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Nootropic Semax, while developed based on the corticotropin 4-10 fragment (ACTH4-10), is a powerful neuro nootropic peptide drug. It was approved by the Government of the Russian Federation in 2011 as part of the list of important and essential medicines in Russia, mainly for the treatment of central nervous system diseases (including stroke, transient ischemic attack, optic nerve disease, etc.), memory and cognitive impairments, and the strengthening of the immune system. While Natural regulatory peptides are usually bioactive compounds produce by various cells. They provide connections between the major regulatory systems of the body, are direct regulatory substances or mediators of most physiological processes occurring in the body, and have a wide range of preventive and therapeutic effects. By modifying the natural regulatory peptide, it can have higher stability, so that it better apply in medical treatment. Nootropic Semax is a synthetic analogue of natural regulatory peptides. What is ACTH? Adrenocorticotropin (ACTH) and its fragments are one of the most active endogenous regulatory peptides. ACTH is a single chain polypeptide compose of 39 amino acids, which form in the anterior pituitary gland through the translation and processing of the precursor proteinogen melanocortin (POMC). ACTH is one of the major regulatory components of the pituitary-hypothalamic axis and interacts with the regulatory system of the hypothalamus. It can enhance the synthesis and secretion of glucocorticoid. In addition to its hormonal effects, ACTH also exhibits a wide range of extra-hormonal activities Multiple studies have shown that ACTH and its fragments can affect the behavior of human and animals. ACTH accelerates the learning process of animals, and it may directly act on the central nervous system without relying on the activity of ACTH hormone. A large number of studies have shown that the N-terminal region of ACTH is the main region responsible for the behavioral activity of hormones, while ACTH4-10 is the smallest fragment that retains the behavioral effect of ACTH molecule. ACTH and its fragments show neuroprotective and neurotrophic effects in addition to the role of puzzle. Studies have shown that even small doses of ACTH can stimulate the growth of nerve fibers. Peripheral nerve regeneration induced by ACTH and ACTH4-10 fragments was accompanied by significant enhancement of neuronal RNA and protein synthesis. ACTH also enhanced RNA and protein synthesis and glucose utilization in the brains of older animals. What is Nootropic Peptide Semax? Product name:Semax Other name:Met-Glu-His-Phe-Pro-Gly-Pro Cas:80714-61-0 , MF:C 37 H 51 N 9 O 10 S MW: 813.93 Purity :≥98% The Origin of Nootropic Semax The discovery of the remarkable intellectual, neuro protective, and neurotrophic effects of ACTH and its fragments makes this peptide one of the most promising candidates for the prevention and treatment of central nervous system diseases. However, these peptides are difficult to use in practice because of their extreme instability and short duration of action. The action time of ACTH4-10 is 30-60 min. After modification of different C- terminal, finding that the analogues carrying three C-terminal amino acids replace by Pro-Gly-Pro sequence show the longest activity. The peptide (h- met-glu-his-phi-pro-gly Pro-OH), is Semax, exhibits the intellectual- promoting effects of the natural prototype, while its action duration (Half- life) lasts 20-24 hours.

Minimum Order: 10 long tons

https://www.astersteroids.com/tirzepatide-a-new-du , al-action-type-ii- diabetes-drug-showed-better- , weight-loss-results-than-semaglultide/ Purity:9 , 8% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Tirzepatide is a drug approved for medical use in the United States, European Union, Canada and Australia for the treatment and control of type 2 diabetes mellitus. As a dual GIP and GLP-1 receptor agonist, it is the first of its kind. What is Tirzepatide for Type 2 Diabetes? The incidence of type 2 diabetes has been on the rise worldwide in recent years, with about 420 million adults worldwide, 30 million people in the United States and 114 million people in China having type 2 diabetes. Globally, one person dies every six seconds from complications related to type 2 diabetes. Type 2 diabetes is the eighth leading cause of death in the world. Obesity and overweight are important risk factors for type 2 diabetes, and about 80-90% of type 2 diabetes patients are overweight or obese. Type 2 diabetes mellitus, also known as non-insulin-dependent diabetes mellitus, is a chronic metabolic disease characterize by pancreatic beta cell dysfunction and insulin resistance. Treatment for this disease focuses on controlling blood sugar, improving insulin resistance and protecting pancreatic beta cell function. The main methods are insulin therapy, oral hypoglycemic drugs, diet control and exercise. A number of drugs used to treat type 2 diabetes are GLP-1 agonists, including Wegovy, Ozempic (Semaglutide), Rybelsus, Saxenda, Trulicity(Dulaglutide) .Peptides Tirzepatide is the latest drugs to treat type 2 diabetes. What is GLP-1? Glucagon-like peptide-1 (GLP-1) is a gastrointestinal hormone that promotes insulin secretion. It has the ability to reduce blood glucose levels in a glucose-dependent manner by enhancing insulin secretion. Natural GLP-1 is usually secrete in the gut after eating. It is susceptible to amidation and proteolytic cleavage and is broken down rapidly in the body, resulting in a known half-life of about 2 minutes. As a result, only 10% to 15% of GLP-1 enters the cycle in its entirety. To overcome this problem, They develop GLP-1 receptor agonists to increase GLP-1 activity. By activating GLP-1 receptor or prolonging the action time of GLP-1, GlP-1- based therapeutic drugs have the multi-effect mechanism of promoting β-cell generation and secretion of insulin, inhibiting α-cell secretion of glucagon, delaying gastric emptying and inhibiting appetite. To control blood sugar levels. At the same time, GLP is glucose-dependent and does not cause severe hypoglycemic symptoms. What is Tirzepatide wight loss? Tirzepatide basic information Cas No.:2023788-19-2 MF:C225H348N48O68 M , W: 4813.527 Bioavailability: 80% Route of administration: subcutaneous Elimination half-life: 5 days Tirzepatide, also known as LY3298176, or Mounjaro, is a linear polypeptide composed of 39 amino acids that has been chemically modified by lipylation to improve its uptake into cells and metabolic stability. In structure, Tirzepatide is an analogue of GIP. Fatty acids are attached to the base of GIP, thus having a longer half-life and higher affinity with albumin. Tirzepatide is a new type II diabetes drug. As an analog of GIP, Tirzepatide plays the similar role of GIP. At the same time, it is also a GLP-1 receptor agonist, which has the dual effects of lowering blood glucose and promoting gastrointestinal function, as well as promoting weight loss.

Minimum Order: 10 long tons

https://www.astersteroids.com/type-2-diabetes-trea , tment-semaglutide- wegovy- fda-approved-for- , heal , thy-weight-loss/ Purity:98% HPLC Packing:2mg/vial and 5mg/vial;10vials/box Min Order: 1box Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country Storage:Shading, confined preservation,2-8°C Peptides Semaglutide is a glucagon-like peptide 1 (GLP-1) receptor agonist. Currently, we know that there are three products approved by the US FDA that contain semaglutide: Ozempic, Rybelsus and Wegovy. Among them, Ozempic and Rybelsus are mainly use for type 2 diabetes, and Wegovy(Semaglutide) use for weight loss. Details as below: What is GLP-1? GLP-1, or glucagon-like peptide-1, is a hormone that naturally producing in the body. It mainly produce in the gut. GLP-1 plays a crucial role in regulating blood sugar levels and appetite. In consuming food, GLP-1releasing into the blood, and it has several effects on the body. Stimulates insulin release: GLP-1 enhances insulin release. Insulin lowers blood sugar levels by encouraging glucose to enter cells. Inhibition of glucagon release: GLP-1 inhibits the release of glucagon, another hormone produced by the pancreas. Glucagon raises blood sugar levels by promoting the release of stored glucose in the liver. Slow gastric emptying: GLP-1 slows the rate at which the stomach dumps its contents into the intestines. This delay in gastric emptying helps reduce the rapid rise in blood sugar levels after a meal. Appetite suppression: GLP-1 acts on the brain to suppress appetite and promote satiety. Given these roles, GLP-1 plays a crucial role in regulating glucose metabolism in the body and promoting glucose control. Development of GLP-1 receptor agonists that can mimic the effects of GLP-1 to improve blood sugar control and weight loss in patients with type 2 diabetes or obesity. That’s what Semaglutide is like. How Semaglutide works? Peptides Semaglutide, first use to treat type 2 diabetes and obesity, acts as a GLP-1 receptor agonist by mimicking GLP-1 action. When inject Semaglutide, it binds to and activates GLP-1 receptors locating on various cells in the body, including pancreatic cells. By stimulating the release of insulin, glucose in the blood encourage to enter cells, thereby lowering blood sugar levels. Sugars that enter the cell also provide energy to the cell; By inhibiting glucagon, the liver does not produce excess glucose, thereby reducing blood sugar levels. By slowing stomach emptying, it reduces the rate at which nutrients, including glucose, are absorbed into the bloodstream, helping to control blood sugar spikes after meals. This effect prevents people from feeling hungry as soon as possible and does not produce the desire to eat, which helps people with type 2 diabetes or obesity control their appetite. Semaglutide also affects appetite regulation centers by acting on the brain, resulting in reduced hunger and increased feelings of gulping. Helps to control appetite and lose weight. Overall, Semaglutide helps improve blood sugar control in people with type 2 diabetes by increasing insulin release, inhibiting glucagon secretion, and slowing digestion, while having the effect of reducing weight control.

Minimum Order: 10 long tons