sell KGF-2 Recombinant Human Keratinocyte Growth Factor-2

Keratinocyte Growth Factor-2 (KGF-2) was originally identified from rat
embryos by

homology-based polymerase chain reaction. Human and mouse KGF-2 were
subsequently cloned. The human KGF-2 cDNA encodes a 208 amino acid residue
protein with a hydrophobic amino-terminal signal peptide. Human KGF-2 shares
approximately 92% and 95% amino acid sequence identity with mouse and rat
KGF-2, respectively. Among the FGF family members, KGF-2 is most closely
related to FGF-7. KGF-2 transcripts has been shown to be most abundant in
the embryo and adult lungs. Recombinant KGF-2 preparations have been shown
to be mitogenic for epithelial and epidermal cells but not fibroblasts.
Based on its in vitro biological activities and in vivo expression pattern,
KGF-2 has been proposed to play unique roles in the brain, in lung
development, wound healing and limb bud formation.

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