sell BFGF

Basic Fibroblast Growth Factor (bFGF) is a member of the FGF family of
mitogenic peptides which is comprised of at least 23 proteins. FGF signaling
factors play a central role during prenatal development and postnatal growth
and regeneration of a variety of tissues, by promoting cellular
proliferation and differentiation. It was originally named bFGF based upon
its chemical properties and to distinguish it from acidic fibroblast growth
factor.



Synonyms: FGF-2, Fibroblast Growth Factor basic (FGFb)

Grade: cosmetic

Source: Escherichia coli

Purity: >95% by SDS-PAGE and HPLC analyses.

Physical Appearance: White lyophilized powder.

Endotoxin: < 1EU/ug of growth factor as determined by LAL method.



AA Sequence MTMITNSSSV PGDPLESMAA GSITTLPALP EDGGSGAFPP GHFKDPKRLY

CKNGGFFLRI HPDGRVDGVR EKSDPHIKLQ LQAEERGVVS IKGVCANRYL

AMKEDGRLLA SKCVTDECFF FERLESNNYN TYRSRKYSSW YVALKRTGQY

KLGPKTGPGQ KAILFLPMSA KS



Molecular Weight: Approximately 18.5 kDa, a single non-glycosylated
polypeptide chain containing 172 amino acids



Biological Activity: Fully biologically active. The ED50 is < 1.0ng/ml,
corresponding to a specific activity of 1.0×106 Units/mg, as determined by
the proliferation of BALB/c 3T3 cells.



Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS,
pH 7.4, containing 4% mannitol.



Reconstitution: Reconstitute in sterile distilled water containing 0.1% BSA
to a concentration of 0.1-1.0 mg/mL.



Storage: Store at -20oC after receiving. Upon reconstitution, store at 2-8oC
for up to one week. For maximal stability, aliquot and store at -20°C.
Avoid repeated freeze/ thaw cycles.

Usage: This product is for research use only. It is not approved for use in
humans, animals, or in vitro diagnostic procedures.

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