minoxidil

White crystals. Melting point is 260°C (decomposition). Slightly soluble in
ethanol and chloroform, almost insoluble in water. Odorless.
use
Antihypertensive drugs for refractory, primary or renal hypertension. Used to
prevent oily hair loss and animal husbandry.
Antihypertensive drugs, used in the treatment of refractory, primary or renal
hypertension. Production method. 4-chloro-2,6-diaminopyrimidine (see 08910) is
obtained by cyclization and chlorination of methyl cyanoacetate. It is then
oxidized with perbenzoic acid to obtain 6-amino-1,2-dihydro-1-hydroxy-2-imino-
4-chloro , pyrimidine (C4H5CIN4O), and finally condensed with hexahydropyridine
to obtain melamine.

Click to Enlarge