Isoquercitrin

Isoquercitrin CAS NO.482-35-9
Product name Isoquercitrin
Another name Quercetin 3-glucoside
Main source Sophora Japonica L.
CAS NO 482-35-9
Isoquercitrin Chemical Formula C21H20O12
Isoquercitrin Molecular Weight 464.38
Specifications 90.0%, 95.0%
Test Method HPLC
Appearance Yellow powder/needle crystal

Isoquercitrin Solubility water soluble<0.1 g/100 at 21 DEG C, soluble in
cold water, soluble in alkali solution deep yellow


Isoquercetin is a flavonoid, a type of chemical compound. Isoquercetin is the
3-O-glucoside of quercetin, which is decomposed enzymatically by Rutin, sourced
from Sophora Japonica L. Isoquercetin has the function of lower blood pressure
and anti-inflammatory effect. There are several kinds of isoquercitrin, such as
enzymatically modified isoquercitrin and alpha glycosyl isoquercitrin, among
which alpha glycosyl isoquercitrin is for allergies.

As a plant extract company, we supply various products of isoquercetin and if
you want to buy isoquercitrin or to know isoquercetin benefits, please contact
us!

Benefits of Isoquercitrin for Health
Isoquercitrin benefits for our health, as following：

1. Isoquercitrin, as a kind of sophora japonica flower extract, has potential
protective effects against oxidative neuronal injuries and brain ischemia.

2. Antidepressant activity.

3. Isoquercitrin has anti-inflammatory effects.

4. With the antidiabetic effect of plant extract, isoquercitrin can prevent
diabetic complications.

5. Isoquercitrin supplement can lower blood levels.

Alpha Glycosyl Isoquercitrin for Allergies
When the seasons turn, it is the peak period of asthma attacks. What should I
do if I don’t want to have asthma and old problems again? In addition to
actively seeking medical treatment and taking medications on time, the daily
diet includes a moderate intake of fresh fruits and vegetables such as onions
and apples to obtain isoquercitrin, which is known as the "natural
antihistamine", and take good care of daily nutrition, which is also a good way
of self-care! Isoquercetin is a "natural antihistamine" that can help fight
asthma and allergic diseases. Nutritionists say that isoquercitrin is a plant-
derived polyphenol component, and polyphenols are used in nutrition. It is
generally considered to be an effective anti-allergic agent. Moderate intake
can affect various biological pathways and immune cell functions in the body's
allergic immune response.

Enzymatically Modified Isoquercitrin for Weight Loss
As a strong antioxidant, foods rich in isoquercitrin are believed to have many
health benefits. Some of the health benefits of isoquercitrin include lowering
blood pressure and blood lipids. Isoquercetin is a rich source of flavonoids in
the diet. Studies have shown that it has the effect of reducing fat and losing
weight. In recent years, the mechanism of isoquercitrin's weight loss effect is
to inhibit the absorption of dietary energy and nutrients, improve the body's
fat metabolism, inhibit the accumulation of triglycerides, promote the
apoptosis of fat cells, and regulate the release of adipokines.

What Are Side Effects of Isoquercitrin?
The common side effects of oral isoquercitrin are numbness in arms and legs;
headache. Very high doses of intravenous isoquercitrin may cause certain side
effects in some people, such as flushing and sweating, nausea and vomiting,
difficulty breathing, kidney damage, etc.

Another possible side effect associated with excessive intake of isoquercitrin
is that it may interfere with thyroid function. In addition to side effects
such as thyroid dysfunction, taking isoquercitrin may also worsen the condition
of patients with kidney disease.

Excessive intake of isoquercitrin may cause many side effects, including
interference with normal thyroid function. Avoid taking quercetin supplements
without the guidance of your healthcare practitioner to avoid side effects.

Isoquercitrin VS Quercetin: What's the Difference?
First of all, quercetin and isoquercitrin, both are natural plant flavonoids.
Quercetin itself has two molecules of bound water (dihydrate), the molecular
formula is C15H10O7+2H2O, so quercetin dihydrate Quercetin is a more stringent
name for quercetin raw materials, but in the determination of quercetin
content, the content of anhydrous quercetin must be calculated, which means
that two molecules of water must be removed from the calculation. From the
perspective of the chemical structure, dihydroquercetin is the reduced form of
quercetin, which is the product of hydrogenating the double bond at positions 2
and 3 in the flavonoid core, with the molecular formula C15H12O7, while
isoquercitrin is a glycoside. Quercetin is an aglycone, which is commonly known
as a glycoside. isoquercitrin is a skeleton with a glucose added with a
molecular formula of C21H20O12. Quercetin and isoquercitrin are both derived
from rutin for desugar treatment. The removal of one sugar (rhamnose) forms
isoquercitrin, and the removal of two sugars (glucose + rhamnose) forms
quercetin. In terms of water solubility, quercetin is insoluble in water and
can only be made into tablets, while dihydroquercetin and isoquercitrin have
better water solubility. In terms of bioavailability, isoquercitrin has been
proven to have a higher bioavailability and faster absorption rate than
quercetin or quercetin (rutin), and its rate is about twice that of quercetin.
It is ten times higher than quercetin (rutin). The glucose part of
isoquercitrin accelerates the uptake of molecules and the conversion to
quercetin.

Technical Data Sheet (TDS) of Isoquercitrin Powder


As a plant extract manufacturer, we will attempt to produce more high quality
products for customers.

Minimum Order: 1 pieces

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