|
Home > Offers to Sell > Chemicals & Plastics > Organic Chemicals > Other Organic Chemicals
Contact: |
icee chang |
Company: |
Astersteroid |
|
no. A13-1 Building 27 Asia Trade Plaza A Wuchang District |
|
Wuhan 43000-0 |
|
China |
Phone: |
17324090758 |
E-Mail: |
|
|
|
Date/Time: |
8/17/23 2:34 GMT |
|
|
GW0742 powder with 99% purity cas:317318-84-6 Benefits
Product link to:https://www.astersteroidS.com/safe-shipping-sar , m , s-gw0742- powder-with-99-purity-cas317318-84-6- , benefits-for-bodybuilding/
Sarms GW0742 Purity:99% HPLC Packing:10g,100g,500g and 1kg Min Order: Powder---10gram Payment:Bitcoin,Moneygram and Wester Union Lead time:24hours after received payment Safe shipping to US and most of Europe country
Product Name: GW0742 CAS:317318-84-6 MF:C21H17F4NO3S2 M , W:471.4846 Appearance: White powder Purity: 99.% min Package: 10g/bag or as customers’request. Test Method: HPLC
When you see below two 2D molecular structure,you must have concerns: What are they? What’s the relationship between them? When we firstly the 2D molecular structure of them,we should think they are the same. If we identify them carefully, we can find the difference between 2D molecular structures is the one F atom. The 2D molecular structure in left without F atom belongs to GW501516,with MF:C21H18F3NO3S2. The 2D molecular structure in right with a F atom belongs to GW0742,with MF: C21H17F4NO3S2. Based on the 2D molecular structure above, we could thought that GW0742 and GW501516 have similar effects. In fact, GW0742 and GW501516 are also PPAR agonists.
So, one f-Atom difference,makes what appearances to these two products? First of all, GW501516 is a relatively mature product. It has been more than 30 years since its initial discovery, while GW0742 is a new product that is still in the research stage. Replacing an H Atom with an F Atom makes GW0742 a new product and a new patent that extends the GW501516 patent, bringing about corresponding economic benefits and providing a new choice for the corresponding users. Second, replacing an H atom with an F atom improves the bioavailability and potency of the drug. A few years ago, chemists discovered that strategically replacing weaker C-H bonds with stronger C-F bonds alleviates or eliminates structural weaknesses in drug molecules, significantly improving their metabolic stability. Although H atom and F Atom are obviously different in some respects, they are comparable in size, so substituting F Atom for H Atom can generally be considered to have little effect on bond (drug) structure. More importantly, due to the different electronic properties of H and F, strategic placement of F Atom can establish additional interactions with its target, thereby increasing the desired activity. Moreover, substituting F into a drug molecule could alter its properties, increasing its bioavailability and making it more easily absorbed by the body.
Minimum Order: 10 grams
Click to Enlarge
SOURCE: Import-Export Bulletin Board (https://www.imexbb.com/)
Post an Offer to Sell
© 1996-2010 IMEXBB.com. All rights reserved.
|
|