Gadopentetate Dimeglumine Injection/API

Since Gadopentetate Dimeglumine Injection was launched in 1992 by Beilu Pharma
in China, it was highly recommended and accepted by the radiologist, and
quickly occupied the market with its excellent quality and reasonable price. Up
to now, linear gadolinium has been safely used for nearly 30 years, with
excellent enhancement effects and few side effects.

Product name: Gadopentetate Dimeglumine Injection

Generic name: Gadopentetate Dimeglumine Injection

Type: Injectable Contrast Media for MRI, Linear Contrast Media

No.1 market share in China

Ingredients: Gadopentetate Dimeglumine

Specification: 10ml:4.69 g; 12ml:5.63 g; 15ml:7.04 g; 20ml:9.38 g

Posology and method of administration: Intravenous injection

Adverse reactions: See the details from the package insert

Shelf life: 36 months

Indication of Gadopentetate Dimegumine Injection
Magnetic resonance imaging of the central nervous system (brain and spinal
cord), abdomen, chest, pelvis, limbs and other human organs and tissues.

Precautions of Gadopentetate Dimegumine Injection
1. Use with caution in patients with severe kidney damage, epilepsy,
hypotension, asthma and other allergic respiratory diseases and those with
allergic tendencies.

2. Take care to avoid the extravasation of the gadopentetic acid liquid during
injection to prevent tissue pain.

3. The serum iron and bilirubin levels of some patients will increase slightly
after medication, but they are asymptomatic and can return to normal within 24
hours.

4. Pregnant women and breastfeeding women should use it with caution. Animal
experiments show that a small amount of medicine liquid enters the milk.

5. The effective enhancement time of Magnevist contrast is 45 minutes. MRI
examination should be performed immediately after intravenous injection.

6. The remaining medicine liquid after one examination should not be used
again.

7. When applying this type of MRI contrast media, follow the relevant safety
regulations in magnetic resonance imaging.

8. GBCAs should be used with caution. When plain scan MRI cannot obtain the
corresponding vital diagnostic information, GBCAs can be used, and the lowest
approved dose is used as much as possible.

9. Gadolinium deposition

Current evidence shows that after repeated use of GBCAs, trace amounts of
gadolinium can remain in the brain and other body tissues. Research reports
have shown that multiple uses of GBCAs can increase the intensity of brain
signals, especially in the dentate nucleus and globus pallidus. Currently,
there are more reports about linear GBCAs and fewer reports about macrocyclic
GBCAs. Animal experiments have shown that the amount of gadolinium deposited
after repeated use of linear GBCAs is higher than that of repeated use of
macrocyclic.

The clinical significance of brain gadolinium deposition is unclear.

In order to minimize the potential risks associated with gadolinium deposition
in the brain, it must be used in strict accordance with the indications and
approved doses. It is recommended to use the lowest approved dose that meets
the requirement of diagnosis and perform a careful benefit-risk assessment and
patient informed communication before repeated administration.

Bei lu is a professional contrast media manufacturing companies, we provide
gadopentetate dimeglumine, mri contrast medium, contrast media products and
etc. Want to know more? Please contact us.

Minimum Order: 20 bags

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