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| Contact: | Contact |
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| Company: | Taizhou Crene Biotechnology Co., Ltd. |
| Add: Economic Developed Zone of Taizhou Zhejiang China. | |
| Taizhou 318000 | |
| China | |
| Phone: | 86-576-88205808 |
| Fax: | 86-576-88205808 |
| E-Mail: |   |
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| Date/Time: | 3/4/22 3:42 GMT |
Cas 1286770-55-5 Verubecestat MK-8931 Synthesis Inhibitors
Chemical Information
Product name:Verubecestat MK-8931 Purity:99% min
CAS NO:1286770-55-5 Solubility:Soluble in DMSO
Molecular Formula:C17H17F2N5O3S Package:Packaging according to customer
requirements
Molecular Weight:409.41 Storage:Store at -20℃
Remarks
MK-8931 is a BACE1 inhibitor. MK-8931 binds significantly to β-secretase.MK-
8931 is a BACE1 inhibitor. MK-8931 binds significantly to β-secretase. target:
BACE1. In vitro:MK-8931 can effectively reduce Aβ40 in cells with a Ki of 7.8
nM and an IC50 of 13 nM. [1] Docking revealed that, with respect to their free
binding energy, acylguanidine 7a has the lowest binding energy followed by MK-
8931 and pioglitazone and binds significantly to β-secretase. [2]
)
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SOURCE: Import-Export Bulletin Board (https://www.imexbb.com/)
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