25-OH Vitamin D

Vitamin D is converted to 25-hydroxyvitamin D (25-OH-VD) by hydroxylation in
the liver and the active 1, 25-dihydroxy vitamin D in the kidneys.

25 hydroxyvitamin D is the main form of vitamin D in the body.

The level of serum vit 25 oh d can reflect the level of vitamin D storage and
correlate with the clinical symptoms of vitamin D deficiency.

Similar to other steroid hormones, 1, 25-dihydroxy vitamin D3 regulates tissue
cell differentiation and related gene expression, mainly regulating blood
calcium level and affecting cell differentiation.

25 0h vitamin d has a high content in blood and a long half-life.

It is stable and is not directly affected by diet and lifestyle. Therefore,
clinical measurement of 25-OH-VD can reflect the proper level of vitamin D in
vivo.

25 OH Vitamin D Intro
25-hydroxyvitamin D is the main form of vitamin D in the body. Vitamin D is a
steroid derivative, is a fat-soluble vitamin, and is a cyclopentane poly hydro
phenanthrene compound. Vitamin D is mainly synthesized by human skin after
being irradiated by ultraviolet rays, and a small part is ingested from food or
supplements. Vitamin D affects calcium and phosphorus metabolism and has a wide
range of physiological effects. It is an indispensable substance for
maintaining human health, cell growth, and development and is closely related
to various diseases. There are two forms of vitamin D in the human body,
vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol), which are
converted to 25-hydroxyvitamin D (25-OH-VD) by hydroxylation in the liver,
which is then converted to active 1,25-dihydroxy vitamin D in the kidneys. The
serum 25-OH-VD can reflect human vitamin D storage level, which is related to
the clinical symptoms of vitamin D deficiency.

Vitamin D Antibody
Vitamin D is an important hormone that regulates calcium and phosphorus
metabolism in the body. The skin mainly synthesizes it under sunlight
conditions, and a small amount can obtain through diet. The active form of
vitamin D is especially 1,25 dihydroxy vitamin D3 (1,25(OH) 2 D 3 ), which
exerts physiological effects by binding to the vitamin D receptor (VDR). 25-
hydroxyvitamin D (25(OH)D) is the body's primary storage form of vitamin D.
1,25(OH)D3 induces the differentiation of monocytes into macrophages and
reduces the release of inflammatory cells and chemokines.

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